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肉桂补充剂对暴饮暴食症患者饮食失调指标的影响:一项随机对照试验。

The effect of cinnamon supplementation on eating disorder indices among people suffering from binge eating disorder: a randomized controlled trial.

作者信息

Gholami Mahan, Mokhtari Ebrahim, Abolghasemi Jamileh, Vafa Mohammadreza

机构信息

Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.

Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

BMC Nutr. 2024 Aug 7;10(1):109. doi: 10.1186/s40795-024-00916-z.

DOI:10.1186/s40795-024-00916-z
PMID:39113092
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11308252/
Abstract

BACKGROUND

Binge eating disorder is one of the main eating disorders that is characterized by recurrent binge eating episodes that lead to complications like high blood pressure, diabetes, dyslipidemia, etc. Many psychological and biological factors can lead to binge eating disorder and one of the main physiological reasons is insulin resistance. Cinnamon is an old favorite that has positive effects on insulin sensitivity. So, we examined the effect of cinnamon on binge eating disorder in this study.

METHODS

This study was conducted on 40 binge eating disorder patients with a BMI between 25 and 39.9 kg/m. They were divided into two groups one of them consumed 6 g of cinnamon per day while the other group consumed 6 g of white wheat as a placebo. Before and after the study we examined weight, height, Body Shape Questionnaire (BSQ), and Binge Eating Scale (BES) scale in all participants and did the statistical analysis.

RESULTS

There were no significant differences in baseline characteristics, gender, height, weight, BMI, education, and marriage status between the two groups. There were no significant changes between BSQ, BES, weight, and height after the study either.

CONCLUSION

According to our findings, although the weight of the patients in the cinnamon group decreased significantly, after the end of the study, no significant difference was observed in the weight, BMI, and BAS and BSQ indices between the two groups.

TRIAL REGISTRATION

The study protocol was registered in the Iran Registry of Clinical Trials (IRCT) center (IRCT code: IRCT20090822002365N26, Registration date: 2021/11/7).

摘要

背景

暴饮暴食症是主要的饮食失调症之一,其特征为反复出现暴饮暴食发作,可导致高血压、糖尿病、血脂异常等并发症。许多心理和生物学因素可导致暴饮暴食症,主要的生理原因之一是胰岛素抵抗。肉桂是一种长期受到青睐的食材,对胰岛素敏感性有积极影响。因此,我们在本研究中考察了肉桂对暴饮暴食症的影响。

方法

本研究针对40名体重指数(BMI)在25至39.9kg/m之间的暴饮暴食症患者开展。他们被分为两组,一组每天食用6克肉桂,另一组食用6克白小麦作为安慰剂。在研究前后,我们对所有参与者的体重、身高、体型问卷(BSQ)和暴饮暴食量表(BES)进行了检测,并进行了统计分析。

结果

两组在基线特征、性别、身高、体重、BMI、教育程度和婚姻状况方面无显著差异。研究结束后,BSQ、BES、体重和身高也无显著变化。

结论

根据我们的研究结果,尽管肉桂组患者的体重显著下降,但在研究结束后,两组在体重、BMI、BAS和BSQ指标方面未观察到显著差异。

试验注册

该研究方案已在伊朗临床试验注册中心(IRCT)注册(IRCT代码:IRCT20090822002365N26,注册日期:2021年11月7日)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef8c/11308252/eeb6ba022bd6/40795_2024_916_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef8c/11308252/eeb6ba022bd6/40795_2024_916_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef8c/11308252/eeb6ba022bd6/40795_2024_916_Fig1_HTML.jpg

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本文引用的文献

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Nutr Rev. 2025 Feb 1;83(2):249-279. doi: 10.1093/nutrit/nuae058.
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Assessment of the potential effects of l-carnitine and cinnamon supplementation on weight loss and body composition.评估左旋肉碱和肉桂补充剂对减肥和身体成分的潜在影响。
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Effects of Cinnamon () Extract on Adipocyte Differentiation in 3T3-L1 Cells and Lipid Accumulation in Mice Fed a High-Fat Diet.
肉桂()提取物对 3T3-L1 细胞脂肪细胞分化和高脂饮食喂养小鼠脂类积累的影响。
Nutrients. 2023 Dec 14;15(24):5110. doi: 10.3390/nu15245110.
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The effects of cinnamon supplementation on adipokines and appetite-regulating hormones: A systematic review of randomized clinical trials.肉桂补充剂对脂肪因子和食欲调节激素的影响:随机临床试验的系统评价
Avicenna J Phytomed. 2023 Sep-Oct;13(5):463-474. doi: 10.22038/AJP.2022.21538.
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Diversity of Binge-Eating Disorder Symptoms Is Associated with Anxiety about Getting Fat Rather Than Body Image: A Clinical Study of Women in Poland.暴食障碍症状的多样性与对发胖的焦虑有关,而不是与身体意象有关:波兰女性的临床研究。
Nutrients. 2023 Oct 27;15(21):4572. doi: 10.3390/nu15214572.
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