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干细胞移植后肠道移植相关微血管病的小肠并发症

Small Intestinal Complications of Intestinal Transplant-Associated Microangiopathy Post-stem Cell Transplantation.

作者信息

Kametaka Daisuke, Iwamuro Masaya, Tanaka Takehiro, Matsuoka Ken-Ichi, Otsuka Motoyuki

机构信息

Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, JPN.

Department of Pathology, Okayama University Hospital, Okayama, JPN.

出版信息

Cureus. 2024 Jul 8;16(7):e64111. doi: 10.7759/cureus.64111. eCollection 2024 Jul.

Abstract

We present the case of a patient who underwent human leukocyte antigen-haploidentical transplantation for T-cell acute lymphoblastic leukemia. Seven weeks after transplantation, the patient developed intestinal transplant-associated microangiopathy (iTAM). Although the iTAM was resolved temporarily, it recurred. Video capsule enteroscopy revealed multiple erosions and shallow ulcers in the jejunum and ileum. To the best of our knowledge, this is the first report to present images of possible small intestinal lesions in iTAM. The small intestinal mucosal images presented herein may potentially aid in the management of similar patients.

摘要

我们报告了一例接受人类白细胞抗原单倍型相合移植治疗T细胞急性淋巴细胞白血病的患者。移植后7周,该患者发生了肠道移植相关微血管病(iTAM)。尽管iTAM暂时得到缓解,但又复发了。视频胶囊内镜检查显示空肠和回肠有多处糜烂和浅溃疡。据我们所知,这是第一份展示iTAM中可能存在的小肠病变图像的报告。本文展示的小肠黏膜图像可能有助于管理类似患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091c/11305607/865085a4e533/cureus-0016-00000064111-i01.jpg

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