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术前扩瞳时间对原发性闭角型青光眼患者白内障超声乳化联合房角切开术效果的影响及其临床意义

Influence of preoperative dilation time on the effect of cataract ultrasonography combined with goniostomy in patients with primary closed angle glaucoma and its clinical significance.

作者信息

Dai Yan, Liu Yuhuan, Dai Anlang, Wang Yaozeng

机构信息

Department of Ophthalmology, Lanzhou Petrochemical General Hospital Lanzhou 730060, Gansu, China.

Department of Anesthesiology, Shenyang Medical College Shenyang 110034, Liaoning, China.

出版信息

Am J Transl Res. 2024 Jul 15;16(7):2889-2897. doi: 10.62347/RMIA8846. eCollection 2024.

Abstract

OBJECTIVE

To evaluate the impact of preoperative pupil dilation time on the outcomes of cataract ultrasonoemulsification combined with goniostomy in patients with primary angle-closure glaucoma (PACG).

METHODS

A retrospective analysis was conducted on 106 PACG patients who underwent cataract ultrasonoemulsification with goniostomy. Patients were divided into two groups based on pupil dilation times: group A (dilation time between 20 to 30 minutes) and group B (dilation time between 30 minutes to 1 hour). Pre- and postoperative intraocular pressure (IOP), visual acuity, pupil diameter, anterior chamber depth (ACD), and lens thickness (LT) were measured. Surgical time and cumulative dissipated energy (CDE) were also analyzed. Multivariate analysis was performed to identify independent risk factors for postoperative complications.

RESULTS

Both groups showed significant postoperative improvement in visual acuity (P < 0.05). Group B exhibited significantly lower postoperative IOP than group A (P < 0.05). There were significant increases in ACD and pupil diameter and a decrease in LT post-dilation in both groups (all P < 0.05). Group B showed a deeper ACD, thinner LT, and larger pupil diameter compared to group A (all P < 0.05). While CDE was similar between groups, operation duration was longer in group A (P < 0.05). Disease course > 5.5 years, preoperative IOP > 25.14 mmHg, pupil diameter before dilation < 4.895 mm, ACD before dilation < 2.105 mm, and dilation time ≤ 30 minutes were independent risk factors for postoperative complications.

CONCLUSION

Preoperative pupil dilation time > 30 minutes leads to better surgical outcome. Several preoperative factors, including dilation time ≤ 30 minutes, are independent risk factors for postoperative complications.

摘要

目的

评估原发性闭角型青光眼(PACG)患者术前瞳孔散大时间对白内障超声乳化联合房角切开术疗效的影响。

方法

对106例行白内障超声乳化联合房角切开术的PACG患者进行回顾性分析。根据瞳孔散大时间将患者分为两组:A组(散大时间为20至30分钟)和B组(散大时间为30分钟至1小时)。测量术前和术后的眼压(IOP)、视力、瞳孔直径、前房深度(ACD)和晶状体厚度(LT)。还分析了手术时间和累积耗散能量(CDE)。进行多因素分析以确定术后并发症的独立危险因素。

结果

两组术后视力均有显著改善(P < 0.05)。B组术后眼压显著低于A组(P < 0.05)。两组散瞳后ACD和瞳孔直径均显著增加,LT均减小(均P < 0.05)。与A组相比,B组ACD更深、LT更薄、瞳孔直径更大(均P < 0.05)。虽然两组间CDE相似,但A组手术时间更长(P < 0.05)。病程> 5.5年、术前眼压> 25.14 mmHg、散瞳前瞳孔直径< 4.895 mm、散瞳前ACD< 2.105 mm以及散瞳时间≤ 30分钟是术后并发症的独立危险因素。

结论

术前瞳孔散大时间> 30分钟可带来更好的手术效果。包括散瞳时间≤ 30分钟在内的几个术前因素是术后并发症的独立危险因素。

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