足月剖宫产新生儿出生即刻过渡期外周肌肉氧饱和度参考范围。
Reference ranges of peripheral-muscle oxygenation in term neonates delivered by Caesarean section during immediate transition after birth.
机构信息
Division of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Research Unit for Neonatal Micro- and Macrocirculation, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
出版信息
Acta Paediatr. 2024 Dec;113(12):2582-2589. doi: 10.1111/apa.17376. Epub 2024 Aug 8.
AIM
To establish reference ranges of peripheral-muscle regional oxygen saturation (prSO) and peripheral fractional tissue oxygen extraction (pFTOE) during the first 15 min after birth in stable term neonates.
METHODS
Secondary outcome parameters of prospective observational studies in healthy term neonates delivered by Caesarean section were analysed. prSO was measured on the right forearm using the INVOS 5100C monitor. pFTOE was calculated out of prSO and arterial oxygen saturation (SpO). Centile charts (10th-90th) of prSO and pFTOE were defined during the first 15 min after birth.
RESULTS
Three-hundred-five term neonates with a mean gestational age and birth weight of 39.0 ± 0.9 weeks and 3321 ± 454 g, respectively, were included. The 50th centiles of prSO were 39% (minute two), 52% (minute five), 71% (minute 10), and 73% (minute 15). The 50th centiles of pFTOE were 0.529 (minute two), 0.378 (minute five), 0.237 (minute 10), and 0.231 (minute 15).
CONCLUSION
Reference ranges of prSO and pFTOE were established for term neonates delivered by Caesarean section during the immediate transition after birth. These reference ranges increase knowledge of physiological processes taking place immediately after birth and are necessary for possible future clinical applications.
目的
建立稳定足月剖宫产新生儿出生后 15 分钟内外周肌肉区域氧饱和度（prSO）和外周组织氧提取分数（pFTOE）的参考范围。
方法
对剖宫产分娩的健康足月新生儿的前瞻性观察研究的次要结局参数进行了分析。使用 INVOS 5100C 监测仪测量右前臂的 prSO。pFTOE 由 prSO 和动脉血氧饱和度（SpO）计算得出。在出生后 15 分钟内定义 prSO 和 pFTOE 的百分位数图表（第 10 至 90 百分位）。
结果
共纳入 305 例胎龄和出生体重分别为 39.0±0.9 周和 3321±454g 的足月新生儿。prSO 的第 50 百分位数分别为出生后第 2 分钟 39%、第 5 分钟 52%、第 10 分钟 71%和第 15 分钟 73%。pFTOE 的第 50 百分位数分别为出生后第 2 分钟 0.529、第 5 分钟 0.378、第 10 分钟 0.237 和第 15 分钟 0.231。
结论
建立了剖宫产分娩的足月新生儿出生后立即过渡期间 prSO 和 pFTOE 的参考范围。这些参考范围增加了对出生后立即发生的生理过程的了解，并且是未来可能的临床应用所必需的。
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