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[移植肾急性乳头坏死]

[Acute papillary necrosis in transplanted kidney].

作者信息

Stefanov G, Minkov N, Patev E, Doĭchinov D, Beleva B

出版信息

Vutr Boles. 1985;24(5):87-90.

PMID:3911582
Abstract

After a short literature survey, indicating the rarity of acute papillary necrosis in transplanted kidneys, the authors reported one of their patients, aged 32, with transplanted dead body kidney from a male, aged 30, with blood group compatibility and compatibility of two antigens in locus A. Two hemodialysis were necessiated because of acute tubular necrosis in the transplant. After the second one, performed 10 days after the transplantation, the patient felt very strong pains in the region of the transplant, edema around it and hypovolemic shock. The kidney was explanted and necrosis of the majority of the papillae in it--established, and around it--blood collection. After that incidence, the patients had three severe gastrointestinal hemorrhages with shocks, that necessitated profuse transfusion of blood. Their cause was a small erosion, about a lentil seed, at the pyloric opening, resulting from the cortico-therapy and periodic heparinization for dialysis. The patients was reanimated and returned to programmed chroniodialysis. The possible causes for papillary necrosis are discussed, most acceptable being two of them them--urostasis from 1200 ml urine in the urinary bladder, that required catheterization before the incidence and/or compression and ischemia of the transplanted kidney by the blood collection around it.

摘要

在进行了简短的文献检索,发现移植肾急性乳头坏死罕见之后,作者报告了他们的一名患者,该患者32岁,接受了一名30岁男性的尸体肾移植,血型相容且A位点有两种抗原相容。由于移植肾急性肾小管坏死,患者需要进行两次血液透析。第二次透析在移植后10天进行,之后患者感到移植部位剧痛,周围出现水肿并发生低血容量性休克。遂将肾脏切除,发现其中大部分乳头坏死,其周围有积血。此次发病后,患者出现三次严重的胃肠道出血并伴有休克,需要大量输血。病因是皮质激素治疗及透析期间定期肝素化导致幽门开口处出现一个约小扁豆大小的糜烂。患者经复苏后恢复了计划性慢性透析。文中讨论了乳头坏死的可能原因,其中最有可能的两个原因是:膀胱内1200毫升尿液导致的尿路淤积,发病前需要进行导尿,和/或移植肾周围的积血对其造成压迫和缺血。

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