Sandow D
Z Gesamte Inn Med. 1985 Nov 15;40(22):661-4.
A clinical relevant diagnostic must be performed early and quickly with sufficient sensitivity and specificity. Under these aspects the virological diagnostics with its methods for the demonstration of viruses as well as for the establishment of an immune response is estimated. As to the proof of pathogenic organisms or antigens is referred to electron-microscopic and immunologic methods (e.g. the fluorescence-antibody-technique, enzyme immunoassay) as well as to the hybridization of nucleic acid. The diagnostics of the immune response is above all based on the demonstration of antibodies. Emphasis is laid on the methods for the establishment of IgM-antibodies, which mostly conclude to an acute virus infection.
必须尽早且迅速地进行具有足够敏感性和特异性的临床相关诊断。从这些方面对病毒学诊断及其用于病毒检测以及免疫反应确立的方法进行评估。至于致病生物体或抗原的检测，涉及电子显微镜和免疫学方法（如荧光抗体技术、酶免疫测定）以及核酸杂交。免疫反应的诊断首先基于抗体的检测。重点在于确立IgM抗体的方法，这些方法大多可判定为急性病毒感染。
