Department of Environmental Science and Engineering, Beijing Technology and Business University, Beijing 100048, China; State Environmental Protection Key Laboratory of Food Chain Pollution Control, Beijing Technology and Business University, Beijing 100048, China.
Institute of Quality Standard and Testing Technology, BAAFS (Beijing Academy of Agriculture and Forestry Sciences), Beijing 100097, China.
Food Chem. 2024 Dec 1;460(Pt 3):140689. doi: 10.1016/j.foodchem.2024.140689. Epub 2024 Jul 31.
Residues of pesticides in milk may pose a threat to human health. This study aimed to develop a liquid-phase microextraction (LPME) method using hexafluoroisopropanol (HFIP)-based supramolecular solvent (SUPRAS) for the simultaneous extraction and purification of four pesticides (boscalid, novaluron, cypermethrin and bifenthrin) in milk. Pesticides were extracted using SUPRAS prepared with nonanol and HFIP, and the extraction efficiency was analyzed. Results showed satisfactory recoveries ranging from 80.8%-111.0%, with relative standard deviations (RSDs) of <6.4%. Additionally, satisfactory linearities were observed, with correlation coefficients >0.9952. The limits of quantification (LOQs) were in the range of 1.8 μg·L-14.0 μg·L. The established method demonstrated high extraction efficiency with a short operation time (15 mins) and low solvent consumption (2.7 mL). The HFIP-based SUPRAS LPME method offers a convenient and efficient approach for the extraction of pesticides from milk, presenting a promising alternative to conventional techniques.
牛奶中的农药残留可能对人类健康构成威胁。本研究旨在开发一种基于六氟异丙醇（HFIP）的超分子溶剂（SUPRAS）的液相微萃取（LPME）方法，用于同时提取和净化牛奶中的四种农药（肟菌酯、唑虫酰胺、氯氰菊酯和联苯菊酯）。使用非醇和 HFIP 制备 SUPRAS 提取农药，并分析萃取效率。结果表明，回收率在 80.8%-111.0%之间，相对标准偏差（RSD）<6.4%。此外，还观察到令人满意的线性关系，相关系数>0.9952。定量限（LOQ）在 1.8μg·L-14.0μg·L 范围内。所建立的方法具有高萃取效率，操作时间短（15 分钟），溶剂消耗低（2.7 毫升）。基于 HFIP 的 SUPRAS LPME 方法为从牛奶中提取农药提供了一种便捷、高效的方法，是传统技术的一种有前途的替代方法。
