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编辑评论:骨软骨异体移植和自体软骨细胞移植都是治疗髌股关节软骨缺损的有价值的选择。

Editorial Commentary: Both Osteochondral Allograft Transplantation and Autologous Chondrocyte Implantation Are Valuable Treatment Options for Patellofemoral Joint Cartilage Defects.

作者信息

Gomoll Andreas H, Strickland Sabrina M

机构信息

New York, New York.

出版信息

Arthroscopy. 2025 Mar;41(3):759-761. doi: 10.1016/j.arthro.2024.07.022. Epub 2024 Aug 8.

Abstract

The patellofemoral (PF) joint is a challenging location to repair cartilage. Although both osteochondral allograft transplantation (OCA) and autologous chondrocyte implantation (ACI) are established as standard therapies for cartilage repair, most treatment algorithms continue to favor ACI for the PF joint, which shows a high rate of success. Today, however, OCA is a treatment of choice to revise prior failed PF cartilage repair. The positive outcomes in this setting encourage indicating OCA for select primary cartilage repair patients, namely those with defects that are uncontained or osteochondral. An advantage of OCA over ACI is that the tissue is more robust and there may be less need for osteotomy to unload the PF joint. Even for ACI, tibial tubercle osteotomy is reserved for patients with abnormal patellar tracking and/or patellar height. In terms of return to sports, realistic expectations are required. Both ACI and OCA are valuable treatment options for PF cartilage defects.

摘要

髌股(PF)关节是软骨修复的一个具有挑战性的部位。尽管骨软骨异体移植(OCA)和自体软骨细胞植入(ACI)都已成为软骨修复的标准疗法,但大多数治疗方案仍倾向于对PF关节采用ACI,其成功率较高。然而如今,OCA是翻修先前失败的PF软骨修复的一种选择。这种情况下的积极结果促使对某些原发性软骨修复患者,即那些存在非包容性或骨软骨缺损的患者,采用OCA治疗。OCA相对于ACI的一个优势在于组织更强健,可能较少需要进行截骨术来减轻PF关节的负荷。即使对于ACI,胫骨结节截骨术也仅适用于髌股轨迹异常和/或髌骨高度异常的患者。在恢复运动方面,需要有现实的预期。ACI和OCA都是治疗PF软骨缺损的有价值的选择。

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