关节内和骨内入路在颞下颌关节靶向注射中的应用:尸体研究。

Intra-articular and intraosseous approach to temporomandibular joint-targeted injections: a cadaveric investigation.

机构信息

Regenerative Medicine Laboratory, Petrópolis Medical School/UNIFASE, Av. Barão do Rio Branco, 1003-Centro, Petrópolis, RJ, 25680-120, Brazil.

Temporomandibular Disorders and Orofacial Pain Service, Petrópolis Medical School/UNIFASE, Petrópolis, Rio de Janeiro, Brazil.

出版信息

J Ultrasound. 2024 Dec;27(4):979-985. doi: 10.1007/s40477-024-00942-4. Epub 2024 Aug 8.

Abstract

PURPOSE

Temporomandibular joint osteoarthritis (TMJ-OA) management is complex, and several conservative and minimally invasive protocols have been proposed. Intra-articular injections of medications directed at OA have been performed, but in some cases, these medications do not directly contact the tissue lesion sites. Here, we propose a new real-time ultrasound-guided technique to inject medications directly into the subchondral bone.

METHODS

Ultrasound image screening was carried out with the point-of-care Clarius L15 device. Then, with the patient's mouth closed, a stainless-steel cannula with a concentric trocar was US-guided using an in-plane approach until the perforating tip of the internal trocar touched the lateral pole of the mandibular condyle. Then, the trocar was inserted through the medullary bone, where a posterior injection was made.

RESULTS

The technique's precision was confirmed by capturing an iodine contrast solution that imaged the medullary condyle of fresh anatomical specimens processed by computed tomography.

CONCLUSION

The proposed technique was effective in accessing the mandibular condyle subchondral bone in the inferior TMJ space for the simultaneously intra-articular (IA) and intra-osseous (IO) in-plane US-guided injections. Thus, its implementation may represent an important advance in early TMJ-OA treatment. This may be a promising approach, especially in OA cases in which the cortical bone is still preserved.

摘要

目的

颞下颌关节骨关节炎(TMJ-OA)的治疗较为复杂,已经提出了几种保守和微创方案。针对 OA 的关节内药物注射已经实施,但在某些情况下,这些药物不能直接接触到组织病变部位。在这里,我们提出了一种新的实时超声引导技术,可将药物直接注射到软骨下骨。

方法

使用即时护理 Clarius L15 设备进行超声图像筛选。然后,在患者闭口的情况下,使用平面内进路,将带有同心套管的不锈钢套管引导至超声,直到内部套管的穿孔尖端触及下颌骨髁突的外侧极。然后,将套管插入骨髓中,进行后向注射。

结果

通过捕获碘对比溶液来确认该技术的精确性,该溶液可对经计算机断层扫描处理的新鲜解剖标本的骨髓髁突进行成像。

结论

所提出的技术可有效地进入下颌髁突软骨下骨,用于在 TMJ 下腔中进行关节内(IA)和骨内(IO)平面内超声引导注射。因此,其实施可能代表了 TMJ-OA 早期治疗的重要进展。对于皮质骨仍保留的 OA 病例,这可能是一种很有前途的方法。

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