Adhikari Roshna, Paudel Mukesh, Jha Ram M, Sah Raman K, Sitaula Saroj, Silwal Prabhat
Department of Radiology, National Academy of Medical Sciences, Bir Hospital.
Department of Anesthesiology, National Academy of Medical Sciences, Bir Hospital, Kathmandu.
Ann Med Surg (Lond). 2024 Jun 21;86(8):4902-4906. doi: 10.1097/MS9.0000000000002301. eCollection 2024 Aug.
Malignancy can lead to colo-enteric fistulas. A malignant fistula between the rectum and the jejunum is a rare occurrence.
A 60-year-old female suffered from diarrhea, vomiting, and epigastric pain for 4 months. After demonstration of a dilated rectum with heterogeneous collection on ultrasonography, contrast-enhanced computed tomography (CECT) along with rectal contrast was done, which showed heterogeneously enhancing asymmetrical circumferential thickening of the proximal rectum, including rectosigmoid junction, collection in the rectum and two recto-jejunal fistulous tracts. Colonoscopy showed ulcero-proliferative growth in the rectum with two fistulous tracts communicating with the jejunum. Biopsy from the growth indicated a poorly differentiated adenocarcinoma. Conservative and palliative treatment was provided.
Clinical features of colo-enteric fistulas can include abdominal pain, diarrhea, and weight loss. The patient may be asymptomatic in some cases. Options for diagnosis include barium studies, enteroscopy, colonoscopy, CECT, and computed tomography enterography (CTE). Malignant bowel fistula is associated with serious complications resulting in high morbidity and mortality rates. Surgical resection and fistula repair are the mainstay of curative treatment.
Long-standing gastrointestinal symptoms like chronic diarrhea in the elderly should be investigated with imaging modalities like CECT. Early detection with imaging can reduce debilitating metabolic and nutritional deficiencies and improve patient's morbidity and mortality.
恶性肿瘤可导致结肠-小肠瘘。直肠与空肠之间的恶性瘘极为罕见。
一名60岁女性腹泻、呕吐及上腹部疼痛4个月。超声检查显示直肠扩张并伴有不均匀积液后,进行了增强计算机断层扫描(CECT)及直肠造影,结果显示直肠近端包括直肠乙状结肠交界处不均匀强化的不对称环形增厚、直肠内积液以及两条直肠-空肠瘘管。结肠镜检查显示直肠有溃疡增生性肿物,有两条瘘管与空肠相通。肿物活检提示低分化腺癌。给予了保守及姑息治疗。
结肠-小肠瘘的临床特征可包括腹痛、腹泻及体重减轻。某些情况下患者可能无症状。诊断方法包括钡剂检查、小肠镜检查、结肠镜检查、CECT及计算机断层扫描小肠造影(CTE)。恶性肠瘘会引发严重并发症,导致高发病率和死亡率。手术切除及瘘管修复是根治性治疗的主要手段。
对于老年人长期存在的胃肠道症状如慢性腹泻,应采用CECT等影像学检查手段进行排查。通过影像学早期发现可减少使人虚弱的代谢及营养缺乏,改善患者的发病率及死亡率。