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继发于黑斑息肉病的回结肠套叠:肿瘤切除手术的必要性。

Ileocolic intussusception secondary to Peutz-Jeghers polyp: the need for oncological resection surgery.

作者信息

Ylli Kristali, Eljack Wala, Hayes Brian, Murphy Thomas

机构信息

Department of Surgery, Mercy University Hospital, Grenville Place, Cork T12 WE28, Ireland.

Department of Histopathology, Cork University Hospital, Wilton, Cork T12 DC4A, Ireland.

出版信息

J Surg Case Rep. 2024 Aug 8;2024(8):rjae489. doi: 10.1093/jscr/rjae489. eCollection 2024 Aug.

DOI:10.1093/jscr/rjae489
PMID:39119533
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11306112/
Abstract

In this case report, we detail the management of a woman in her late 30s with ileocolic intussusception, emphasizing the high malignancy risk inherent in adult intussusception cases. Given the patient's acute symptoms and significant family history of ovarian and breast cancers, radical oncological resection was pursued. The surgical intervention comprised a right hemicolectomy and right ovarian cystectomy, with histopathological findings revealing a Peutz-Jeghers polyp and benign thyroid tissue, but no malignancy. This case underscores the imperative for a surgical approach that anticipates the potential for malignancy in adult intussusception, advocating for radical resection as a fundamental strategy, even in the absence of confirmed malignant histopathology, to ensure comprehensive management and alignment with oncological best practices.

摘要

在本病例报告中,我们详细介绍了一名30多岁晚期女性回结肠套叠的治疗情况,强调了成人套叠病例中固有的高恶性风险。鉴于患者的急性症状以及卵巢癌和乳腺癌的重要家族史,我们进行了根治性肿瘤切除术。手术干预包括右半结肠切除术和右卵巢囊肿切除术,组织病理学检查结果显示为黑斑息肉病息肉和良性甲状腺组织,但未发现恶性肿瘤。该病例强调了对于成人套叠采取手术方法时必须考虑到潜在恶性肿瘤的必要性,主张即使在未确诊恶性组织病理学的情况下,根治性切除作为基本策略,以确保全面治疗并符合肿瘤学最佳实践。

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Ileocolic intussusception secondary to Peutz-Jeghers polyp: the need for oncological resection surgery.继发于黑斑息肉病的回结肠套叠:肿瘤切除手术的必要性。
J Surg Case Rep. 2024 Aug 8;2024(8):rjae489. doi: 10.1093/jscr/rjae489. eCollection 2024 Aug.
2
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本文引用的文献

1
Clinical Guidelines for Diagnosis and Management of Peutz-Jeghers Syndrome in Children and Adults.儿童和成人皮杰特-杰格斯综合征的诊断和管理临床指南。
Digestion. 2023;104(5):335-347. doi: 10.1159/000529799. Epub 2023 Apr 13.
2
Solitary Peutz-Jeghers Type Polyp of Jejunum with Gastric Fundic and Antral Gland Lining Mucosa: A Case Report and Review of Literature.孤立性空肠型肠息肉病伴胃底和贲门黏膜腺体:病例报告及文献复习。
Int J Surg Pathol. 2022 Aug;30(5):539-542. doi: 10.1177/10668969211067760. Epub 2021 Dec 27.
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Bowel intussusception in adult: Prevalence, diagnostic tools and therapy.
成人肠套叠:患病率、诊断工具及治疗
World J Methodol. 2021 May 20;11(3):81-87. doi: 10.5662/wjm.v11.i3.81.
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Peutz-Jeghers syndrome.皮杰特-杰格斯综合征。
Curr Opin Gastroenterol. 2021 May 1;37(3):245-254. doi: 10.1097/MOG.0000000000000718.
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Most Adult Intussusceptions are Caused by Tumors: A Single-Centre Analysis.大多数成人肠套叠由肿瘤引起:一项单中心分析
Cancer Manag Res. 2020 Oct 12;12:10011-10015. doi: 10.2147/CMAR.S268921. eCollection 2020.
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Adult intussusception: a systematic review and meta-analysis.成人肠套叠:系统评价和荟萃分析。
Tech Coloproctol. 2019 Apr;23(4):315-324. doi: 10.1007/s10151-019-01980-5. Epub 2019 Apr 22.
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Intestinal Intussusception: Etiology, Diagnosis, and Treatment.肠套叠:病因、诊断与治疗
Clin Colon Rectal Surg. 2017 Feb;30(1):30-39. doi: 10.1055/s-0036-1593429.
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Intestinal intussusception.肠套叠
Clin Colon Rectal Surg. 2008 May;21(2):106-13. doi: 10.1055/s-2008-1075859.
9
Intussusception of the bowel in adults: a review.成人肠套叠:综述
World J Gastroenterol. 2009 Jan 28;15(4):407-11. doi: 10.3748/wjg.15.407.
10
Intussusception in adults: an unusual and challenging condition for surgeons.成人肠套叠:对外科医生来说是一种罕见且具有挑战性的病症。
Int J Colorectal Dis. 2005 Sep;20(5):452-6. doi: 10.1007/s00384-004-0713-2. Epub 2005 Mar 10.