2006 年至 2022 年澳大利亚国家结直肠癌筛查计划中的纵向筛查依从性。

Longitudinal screening adherence in the Australian National Bowel Cancer Screening Program from 2006 to 2022.

机构信息

The Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Australia.

出版信息

Prev Med. 2024 Sep;186:108095. doi: 10.1016/j.ypmed.2024.108095. Epub 2024 Aug 8.

DOI:10.1016/j.ypmed.2024.108095

PMID:39122018

Abstract

OBJECTIVE

Australia's National Bowel Cancer Screening Program (NBCSP) offers two-yearly screening to 50-74-year-olds for the prevention and early detection of colorectal cancer (CRC). Internationally, detailed reporting of participation across multiple screening rounds - also known as longitudinal adherence - is becoming more common, but remains limited in Australia. We described the longitudinal screening adherence of individuals by age and sex invited to the NBCSP at least once, and quantified longitudinal adherence among individuals who received four NBCSP invitations.

METHODS

We obtained aggregate national data for individuals who received at least one NBCSP invitation between 1 August 2006 and 31 March 2022. We described screening adherence patterns including longitudinal adherence among individuals who received four invitations, and evaluated prior longitudinal adherence and adherence at most recent invitation as predictors of future participation.

RESULTS

Over the study period, 8.5 million individuals were invited to screen in the NBCSP; 51.9% of these individuals screened at least once. Of the >2.5 million individuals who received four invitations, 23.3% consistently screened, 38.3% never screened, and 38.3% inconsistently screened. The longitudinal adherence at the fourth invitation round for individuals who previously returned none, one, two, or three of their previous three invitations was 9.5%, 37.4%, 70.1% and 88.8%, respectively. Both longitudinal adherence and adherence at the most recent invitation were significant predictors of future participation.

CONCLUSION

Our study is the first detailed report of longitudinal adherence to the NBCSP in >2 screening rounds. These insights into long-term behaviours can inform planning for interventions to improve screening participation.

摘要

目的

澳大利亚国家结直肠癌筛查计划（NBCSP）为 50-74 岁人群提供两年一次的筛查，以预防和早期发现结直肠癌（CRC）。在国际上，对多次筛查轮次的参与情况（也称为纵向依从性）进行详细报告的情况越来越普遍，但在澳大利亚仍很有限。我们按年龄和性别描述了至少被邀请参加 NBCSP 一次的个体的纵向筛查依从性，并量化了收到 NBCSP 四次邀请的个体的纵向依从性。

方法

我们获得了至少收到一次 NBCSP 邀请的个体的全国汇总数据，这些邀请是在 2006 年 8 月 1 日至 2022 年 3 月 31 日之间发出的。我们描述了筛查依从模式，包括收到四次邀请的个体的纵向依从性，并评估了先前的纵向依从性和最近一次邀请时的依从性作为未来参与的预测因素。

结果

在研究期间，有 850 万人被邀请参加 NBCSP 筛查；其中 51.9%的人至少筛查过一次。在收到四次邀请的>250 万人中，23.3%的人持续筛查，38.3%的人从未筛查，38.3%的人不规律筛查。对于以前没有返回过前三次邀请中的任何一次、一次、两次或三次邀请的个体，第四次邀请轮次的纵向依从性分别为 9.5%、37.4%、70.1%和 88.8%。纵向依从性和最近一次邀请时的依从性都是未来参与的显著预测因素。