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孕23 + 0周后稽留流产患者的管理及结局评估:一项回顾性队列研究

Evaluation of the Management and Outcome of Patients with Retained Products of Conception after Gestational Week 23+0: A Retrospective Cohort Study.

作者信息

Pateisky Petra, Mikula Fanny, Adamovic Marija, Neumüller Jana, Chalubinski Kinga, Falcone Veronica, Springer Stephanie

机构信息

Department of Obstetrics and Gynecology, Division of Obstetrics and Feto-Maternal Medicine, Medical University of Vienna, 1090 Vienna, Austria.

出版信息

J Clin Med. 2024 Jul 29;13(15):4439. doi: 10.3390/jcm13154439.

Abstract

Retained products of conception after childbirth or miscarriage are associated with an increased rate of maternal complications, such as abnormal vaginal bleeding and infections. Late complications may also include intrauterine adhesions, causing infertility. Surgical interventions carry a certain risk. Thus, conservative management is often discussed as an alternative. The aim of this study was to assess the clinical outcomes of patients with retained products of conception, comparing a primary surgical approach to conservative management. We conducted a retrospective cohort study of 88 patients diagnosed with retained products of conception after 23+0 weeks of gestation at the Medical University Vienna between 2014 and 2022. Forty-seven (53.4%) patients underwent primary surgical management and 41 (46.6%) primary conservative management. After primary conservative treatment, a complication could be observed in 10 (24.4%) women. In contrast, complications occurred in 32 (68.1%) women in the group with primary surgical treatment ( < 0.001). The most common complication in both groups was the ongoing suspicion of retained products of conception. Patients after primary surgical treatment were significantly more likely to require a secondary change in treatment ( < 0.001). Ultimately, secondary conservative management was applied in 30 (63.8%) patients. In contrast, only nine (21.95%) patients with primary conservative management required secondary surgical management. Due to the high risk of complications and persistent retained products of conception, primary surgical management should only be prioritized in hemodynamically instable or septic patients.

摘要

分娩或流产后残留的妊娠产物与孕产妇并发症发生率增加有关,如异常阴道出血和感染。晚期并发症还可能包括宫腔粘连,导致不孕。手术干预存在一定风险。因此,保守治疗常被作为一种替代方案进行讨论。本研究的目的是评估妊娠产物残留患者的临床结局,比较初次手术治疗与保守治疗的效果。我们对2014年至2022年期间在维也纳医科大学诊断为妊娠23+0周后妊娠产物残留的88例患者进行了一项回顾性队列研究。47例(53.4%)患者接受了初次手术治疗,41例(46.6%)接受了初次保守治疗。初次保守治疗后,10例(24.4%)女性出现了并发症。相比之下,初次手术治疗组有32例(68.1%)女性出现了并发症(<0.001)。两组最常见的并发症都是持续怀疑有妊娠产物残留。初次手术治疗后的患者更有可能需要进行二次治疗调整(<0.001)。最终,30例(63.8%)患者接受了二次保守治疗。相比之下,初次保守治疗的患者中只有9例(21.95%)需要二次手术治疗。由于并发症风险高且妊娠产物持续残留,初次手术治疗仅应优先用于血流动力学不稳定或感染性患者。

相似文献

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Medical management of retained products of conception: A prospective observational study.《胎物残留的医学处理:一项前瞻性观察研究》
Eur J Obstet Gynecol Reprod Biol. 2023 Jun;285:153-158. doi: 10.1016/j.ejogrb.2023.04.012. Epub 2023 Apr 18.

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