Insular amyloidosis and diabetes mellitus in a crab-eating macaque (Macaca fascicularis).

Clinicopathologic examination of a crab-eating macaque (Macaca fascicularis) with chronic weight loss and bilateral cataracts revealed high fasting serum glucose, glucosuria and hypercholesterolemia. Clinical signs were eliminated by treatment once a day with isophane insulin suspension. Extensive insular amyloidosis was found microscopically sixty days later.