HPV 相关的鼻窦鳞状细胞癌伴 FGFR3::TACC3 融合。一例罕见病例报告。
HPV- associated sinonasal squamous cell carcinoma with FGFR3::TACC3 fusion. A rare case report.
机构信息
Department of Cellular Pathology, Leeds Teaching Hospitals NHS Trust, UK.
ENT Department, Leeds Teaching Hospitals NHS Trust, UK.
出版信息
Oral Oncol. 2024 Oct;157:106983. doi: 10.1016/j.oraloncology.2024.106983. Epub 2024 Aug 9.
Abstract
Sinonasal squamous cell carcinomas (SNSCCs) are uncommon and they are associated with adverse prognosis. HPV-associated SNSCCs and fusion-driven SNSCCs are particularly rare. A case of an HPV-associated SNSCC with a FGFR3::TACC3 fusion is thus presented; a brief review of the pertinent literature is also provided.
摘要
鼻腔鼻窦鳞状细胞癌（SNSCC）较为少见，且预后不良。HPV 相关的 SNSCC 和融合驱动的 SNSCC 则更为罕见。本文报道了一例 HPV 相关的 SNSCC 合并 FGFR3::TACC3 融合，并对相关文献进行了简要回顾。
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