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应用振幅整合脑电图和 GMs 量表评估高危脑损伤早产儿的神经功能恢复情况。

Assessment of neural function recovery in premature infants at high risk of brain injury using amplitude integrated electroencephalography and GMs scales.

机构信息

Department of Rehabilitation Medicine, Northern Jiangsu People's Hospital Affiliated to Yangzhou University (Clinical Medical College, Yangzhou University), 225002, China.

Department of Rehabilitation Medicine, Northern Jiangsu People's Hospital Affiliated to Yangzhou University (Clinical Medical College, Yangzhou University), 225002, China.

出版信息

J Neurosci Methods. 2024 Oct;410:110246. doi: 10.1016/j.jneumeth.2024.110246. Epub 2024 Aug 8.

DOI:10.1016/j.jneumeth.2024.110246
PMID:39127351
Abstract

Preterm infants are a high-risk group for brain injury, and it is important to evaluate the neurological recovery of preterm infants. Therefore, this paper evaluates the neurological recovery in preterm infants at high risk of brain injury by amplitude-integrated EEG and GMs scale. The study collected basic information on preterm infants and performed amplitude integrated EEG examination and GMs scale evaluation. Amplitude integrated EEG examination attaches electrodes using multielectrode arrays onto specific areas of the premature head to record brain wave activity to monitor electrical activity in the preterm brain in real time and amplify and process through the signals received by the electrodes to obtain more detailed EEG data. The GMs scale evaluates the developmental and functional status of the child and allows an objective assessment of the development and recovery of neurological function by observing their performance in motor, language, cognition, and social interaction. Analysis of the data by statistical processing. The results showed that early brain injury was evident in high-risk infants. Amplitude integrated EEG parameters can have some predictive value for brain injury. There were also differences in GMs scale assessment between brain injury and non-brain injury. Amplitude integrated EEG combined with GMs scale has certain value in predicting brain injury and can provide an important basis for early intervention in children with preterm brain injury and help to improve their neurodevelopmental outcome.

摘要

早产儿是脑损伤的高危人群,评估早产儿的神经恢复情况非常重要。因此,本文通过振幅整合脑电图和 GMs 评分来评估有脑损伤高危风险的早产儿的神经恢复情况。该研究收集了早产儿的基本信息,并进行了振幅整合脑电图检查和 GMs 评分评估。振幅整合脑电图检查使用多电极阵列将电极贴在早产儿头部的特定区域,以记录脑电波活动,实时监测早产儿大脑的电活动,并通过电极接收的信号进行放大和处理,以获得更详细的 EEG 数据。GMs 评分评估儿童的发育和功能状态,通过观察他们在运动、语言、认知和社会互动方面的表现,对神经功能的发育和恢复进行客观评估。通过统计处理对数据进行分析。结果表明,高危婴儿存在早期脑损伤,振幅整合脑电图参数对脑损伤有一定的预测价值。脑损伤组和非脑损伤组在 GMs 评分评估方面也存在差异。振幅整合脑电图结合 GMs 评分在预测脑损伤方面具有一定的价值,可以为早产儿脑损伤的早期干预提供重要依据,有助于改善其神经发育结局。

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