J Am Pharm Assoc (2003). 2024 Jul-Aug;64(4S):102174. doi: 10.1016/j.japh.2024.102174. Epub 2024 Aug 10.
Pre-exposure prophylaxis (PrEP) is highly effective at reducing the risk of human immunodeficiency virus (HIV) acquisition in at-risk individuals; however, it is largely underutilized. The Veterans Health Administration has created an HIV PrEP dashboard to identify at-risk veterans in attempt to increase PrEP enrollment.
This study aimed to determine whether the use of an HIV PrEP dashboard would prove effective at increasing PrEP enrollment at a single facility.
This was a single-center quality improvement project. Three pharmacists used the HIV PrEP dashboard and retrospective chart review to identify eligible patients for PrEP. A multimodal process of contacting patients was conducted. The primary objective was to evaluate the number of patients who enrolled in PrEP during the study period. Secondary objectives included evaluating the ability of the HIV PrEP dashboard to identify eligible patients, identify effective strategies to target PrEP enrollment, and compare those patients who accepted with those who declined PrEP to evaluate barriers to enrollment.
Of the 94 patients reviewed, 26 patients (27.7%) were found eligible for PrEP. Of the eligible patients, 3 patients (11.5%) were enrolled, and 7 patients (26.9%) declined PrEP. The others were lost to follow-up (9 of 26, 34.6%), had no action taken on a chart note to provider (6 of 26, 23.1%), or did not have a primary care provider assigned at the local facility (1 of 26, 3.9%). The 3 patients who were successfully enrolled in PrEP were all contacted and prescribed PrEP through the infectious diseases (ID) clinic. There were no statistically significant differences between the cohorts of patients who accepted and declined PrEP.
The use of an HIV PrEP dashboard aided in identifying eligible patients for PrEP. Enrollment through the ID clinic was the most successful modality. Further research is needed to characterize barriers to PrEP uptake and to develop strategies to increase prescribing from non-ID providers.
暴露前预防(PrEP)在降低高危人群感染人类免疫缺陷病毒(HIV)的风险方面非常有效;然而,它的利用率还很低。退伍军人健康管理局创建了一个 HIV PrEP 仪表盘,以识别有风险的退伍军人,试图增加 PrEP 的登记人数。
本研究旨在确定在单一机构使用 HIV PrEP 仪表盘是否能有效增加 PrEP 的登记人数。
这是一项单中心质量改进项目。三名药剂师使用 HIV PrEP 仪表盘和回顾性图表审查来确定符合 PrEP 条件的患者。采用多模式的患者联系流程。主要目标是评估在研究期间登记参加 PrEP 的患者人数。次要目标包括评估 HIV PrEP 仪表盘识别合格患者的能力、确定针对 PrEP 登记的有效策略,并比较接受和拒绝 PrEP 的患者,以评估登记障碍。
在审查的 94 名患者中,有 26 名(27.7%)患者被发现符合 PrEP 条件。在符合条件的患者中,有 3 名(11.5%)患者参加了 PrEP,有 7 名(26.9%)患者拒绝了 PrEP。其余的人失去了随访(26 人中的 9 人,34.6%),有 26 人中的 6 人(23.1%)没有在图表记录上采取行动,或在当地机构没有指定初级保健提供者(26 人中的 1 人,3.9%)。成功登记参加 PrEP 的 3 名患者都是通过传染病科(ID)诊所联系并开了 PrEP 处方。接受和拒绝 PrEP 的患者队列之间没有统计学上的显著差异。
使用 HIV PrEP 仪表盘有助于确定符合 PrEP 条件的患者。通过 ID 诊所登记是最成功的模式。需要进一步研究以确定 PrEP 采用的障碍,并制定增加非 ID 提供者处方的策略。