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一个被错过的诺贝尔奖:苏巴斯·穆克霍帕德希亚博士(1931 - 1981),印度试管婴儿之父。

A missed Nobel: Dr Subhas Mukhopadhyay (1931-1981), the Father of Indian IVF.

作者信息

Khastgir Gaurav, Khastgir Gautam

机构信息

Department of Obstetrics & Gynaecology, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.

Bengal Infertility & Reproductive Therapy Hospital (BIRTH), Kolkata, West Bengal, India.

出版信息

J Med Biogr. 2025 May;33(2):105-108. doi: 10.1177/09677720241273560. Epub 2024 Aug 11.

Abstract

The Indian journey of assisted reproductive therapy began in Calcutta on 3 October 1978, when Dr Subhas Mukhopadhyay discovered the technique of in vitro fertilisation (IVF) only 67 days following the birth of the world's first IVF baby, Louise Brown in the United Kingdom by Edwards and Steptoe. While Edwards won the Nobel Prize in 2010 for his groundbreaking work, Mukhopadhyay, the man behind the genesis of 'Durga', India's first IVF baby, never received any recognition. Instead, he faced severe humiliation from his peers. His colleagues and the government dismissed his claims and unable to live with dishonour and disgrace, he tragically took his life on 19 June 1981. Today his innovative techniques of cryopreservation, gonadotropin stimulation and transvaginal oocyte retrieval are used worldwide across millions of fertility clinics, helping childless couples live the dream of parenthood.

摘要

印度的辅助生殖治疗之旅始于1978年10月3日的加尔各答,当时苏巴斯·穆克霍帕德希亚医生发现了体外受精(IVF)技术,此时距离世界上首例体外受精婴儿路易丝·布朗在英国由爱德华兹和斯特普托接生仅过去了67天。虽然爱德华兹因开创性工作于2010年获得诺贝尔奖,但印度首例体外受精婴儿“杜尔加”诞生背后的功臣穆克霍帕德希亚却从未得到任何认可。相反,他遭到了同行的严厉羞辱。他的同事和政府驳回了他的说法,因无法忍受耻辱,他于1981年6月19日 tragically 自杀。如今,他的冷冻保存、促性腺激素刺激和经阴道取卵等创新技术在全球数百万家生育诊所中得到应用,帮助无子女夫妇实现为人父母的梦想。

相似文献

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In vitro fertilization: four decades of reflections and promises.体外受精:四十年的回顾与展望。
Biochim Biophys Acta. 2011 Sep;1810(9):843-52. doi: 10.1016/j.bbagen.2011.05.001. Epub 2011 May 13.
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The early days of IVF outside the UK.英国以外地区体外受精的早期发展
Hum Reprod Update. 2005 Sep-Oct;11(5):439-59. doi: 10.1093/humupd/dmi016. Epub 2005 May 27.

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