Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Nationwide Children's Hospital, Columbus, Ohio, USA.
The Ohio State University College of Medicine, Columbus, Ohio, USA.
J Pediatr Gastroenterol Nutr. 2024 Oct;79(4):850-854. doi: 10.1002/jpn3.12345. Epub 2024 Aug 11.
Rumination syndrome (RS) is challenging to diagnose, which can lead to diagnostic delays. Our objective was to evaluate the length of time from RS symptom onset to diagnosis in patients referred to our institution and to examine whether this duration predicts treatment outcomes.
We conducted a review of patients with RS evaluated at our institution. Data were collected from chart review and patient/family reported questionnaires. We evaluated the time from symptom onset to diagnosis over time and whether it was associated with symptom resolution.
We included 247 patients with RS (60% female, median age of 14 years, interquartile range [IQR]: 9-16 years). The median age at symptom onset was 11 years (IQR: 5-14 years) and median age at diagnosis was 13 years (IQR: 9-15 years) for a median duration of 1 year (IQR: 0-3 years) between symptom onset and diagnosis. Length of time between symptom onset and diagnosis did not change significantly at our institution from 2016 to 2022. Among the 164 children with outcome data, 47 (29%) met criteria for symptom resolution after treatment. A longer time to diagnosis was associated with a lower likelihood of symptom resolution after treatment (p = 0.01).
In our experience, the time to RS diagnosis after symptom onset is shorter than previously described. A longer delay in diagnosis is associated with lower likelihood of symptom resolution after treatment, emphasizing the importance of a prompt recognition of rumination symptoms and a timely diagnosis.
反刍综合征（RS）的诊断具有挑战性，这可能导致诊断延迟。我们的目的是评估患者就诊于我院后从 RS 症状出现到诊断的时间，并研究该持续时间是否可预测治疗结果。
我们对我院评估的 RS 患者进行了回顾性研究。数据来自病历回顾和患者/家属报告的问卷。我们评估了随时间推移 RS 症状出现到诊断的时间，并研究其是否与症状缓解相关。
共纳入 247 例 RS 患者（60%为女性，中位年龄为 14 岁，四分位距 [IQR]：9-16 岁）。症状出现的中位年龄为 11 岁（IQR：5-14 岁），诊断的中位年龄为 13 岁（IQR：9-15 岁），症状出现到诊断的中位时间为 1 年（IQR：0-3 年）。自 2016 年至 2022 年，我院 RS 患者症状出现到诊断的时间无明显变化。在有结局数据的 164 例儿童中，47 例（29%）经治疗后符合症状缓解标准。诊断时间延长与治疗后症状缓解可能性降低相关（p=0.01）。
在我们的经验中，RS 症状出现后到诊断的时间比之前描述的要短。诊断时间延长与治疗后症状缓解可能性降低相关，这强调了及时识别反刍症状和及时诊断的重要性。
