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作者信息

Garba Aziz Abdoul, Solo Traore, Diongole Hassane Moussa, M Awalou Abassi Ibrahim, Mamane Daou, Brah Souleymane

机构信息

Clinical Research and Health System Laboratory (LaReCSS), Internal Medicine Department, Zinder National Hospital, Faculty of Health Sciences, André Saliou University, Zinder, Niger.

Department of Internal Medicine, Ziniaré Regional Hospital, Burkina Faso.

出版信息

Tunis Med. 2024 Aug 5;102(8):483-490. doi: 10.62438/tunismed.v102i8.4635.

Abstract

OBJECTIVE

To describe the epidemiological, clinical, paraclinical, therapeutic and evolutionary characteristics of of peripartum cardiomyopathy (PPCM) in the internal medicine department of the Zinder National Hospital (ZNH).

METHODS

This was a descriptive cross-sectional study carried out from 2018 to 2022 at the ZNH Department of Internal Medicine. Included were all patients admitted for PPCM who met National Heart Blood and Lung Institute criteria. The data collected was analyzed using Excel and EPI INFO v7.

RESULTS

We had collected 100 cases of PPCM out of a total of 8706 hospitalized patients, i.e. a hospital prevalence of 1.14%. The mean age of the patients was 27.9 years ± 7.4 [17-45]. The majority of patients were from underprivileged social strata (n=64). The risk factors for PMPC found were essentially hot bath (n=66), home birth (n=40), natron porridge (n=35) and multiparity (n=57). Cardiac symptomatology appeared postpartum in 56% of patients. Dyspnea was the main symptom in 98% of cases. The physical signs were dominated by the functional systolic murmur (66%). Three quarters (75%) of the patients had congestive heart failure. Electrocardiographic signs were dominated by left ventricular hypertrophy (n=65). Cardiomegaly was present in 94% of patients. Left ventricular ejection fraction was altered in all patients. Impaired renal function was found in 31% of patients. Management was based on a low-sodium diet tripod, diuretics and converting enzyme inhibitors. Two cases of death were recorded.

CONCLUSION

PPCM is common in the Zinder region. It affects young women with several risk factors and is revealed by signs of congestive heart failure. For a better understanding of this still poorly elucidated condition, it is necessary to pursue research efforts.

摘要

目的

描述津德尔国家医院内科围产期心肌病(PPCM)的流行病学、临床、辅助检查、治疗及演变特征。

方法

这是一项于2018年至2022年在津德尔国家医院内科开展的描述性横断面研究。纳入所有符合美国国立心肺血液研究所标准的因PPCM入院的患者。收集的数据使用Excel和EPI INFO v7进行分析。

结果

在总共8706例住院患者中,我们收集到100例PPCM病例,即医院患病率为1.14%。患者的平均年龄为27.9岁±7.4岁[17 - 45岁]。大多数患者来自贫困社会阶层(n = 64)。发现的PMPC危险因素主要有热水浴(n = 66)、在家分娩(n = 40)、泡碱粥(n = 35)和多胎妊娠(n = 57)。56%的患者产后出现心脏症状。98%的病例中,呼吸困难是主要症状。体征以功能性收缩期杂音为主(66%)。四分之三(75%)的患者有充血性心力衰竭。心电图表现以左心室肥厚为主(n = 65)。94%的患者有心脏扩大。所有患者左心室射血分数均有改变。31%的患者肾功能受损。治疗基于低盐饮食、利尿剂和转换酶抑制剂。记录到2例死亡病例。

结论

PPCM在津德尔地区很常见。它影响有多种危险因素的年轻女性,并以充血性心力衰竭症状为表现。为了更好地理解这种仍未完全阐明的疾病,有必要继续开展研究工作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c200/11390063/8cd1eddc1149/capture1.jpg

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