Jain Ayushi, Chundawat Prashasti, Gupta Shalini, Ram Hari
Dept of Oral Pathology, Microbiology and Forensic Odontology, King George's Medical University, Lucknow, 226003 India.
Dept of Oral & Maxillofacial Surgery, King George's Medical University, Lucknow, 226003 India.
Indian J Otolaryngol Head Neck Surg. 2024 Aug;76(4):3537-3542. doi: 10.1007/s12070-024-04600-3. Epub 2024 Mar 14.
Giant cell tumor (GCT) is a benign, locally aggressive neoplasm with a high recurrence rate with common occurrence in the long bone and the cases in the maxillofacial region bone are very rare. Due to the paucity of the cases, there is not enough information available regarding the behavior of the tumor. Also, the differentiation of this aggressive lesion with the commonly occurring reactive giant cell lesions is crucial and needs more research. This study is pertaining to the review of literature of the cases of GCT in the oral cavity with their clinicopathological, radiographic, and biochemical analyses. Although there are no available studies regarding the immunohistochemical characteristics of this lesion, this study is the first step in this direction to differentiate this tumor better and identify the possible pathogenesis.
骨巨细胞瘤（GCT）是一种良性、具有局部侵袭性的肿瘤，复发率高，常见于长骨，而发生于颌面部骨骼的病例非常罕见。由于病例稀少，关于该肿瘤的行为尚无足够信息。此外，鉴别这种侵袭性病变与常见的反应性巨细胞病变至关重要，且需要更多研究。本研究旨在回顾口腔骨巨细胞瘤病例的文献，并进行临床病理、影像学和生化分析。尽管目前尚无关于该病变免疫组化特征的研究，但本研究是朝这个方向迈出的第一步，以更好地鉴别该肿瘤并确定可能的发病机制。
