Erfanian Reza, Mohebbi Mahdieh, Abdullah Hakima, Sadeghniiat-Haghighi Khosro, Najafi Arezu, Heidari Reihaneh, Mousavi-Asl Benyamin
Otolaryngology research center, Tehran University of Medical Sciences, Tehran, Iran.
Occupational Sleep Research Center, Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Indian J Otolaryngol Head Neck Surg. 2024 Aug;76(4):2981-2986. doi: 10.1007/s12070-024-04731-7. Epub 2024 May 2.
BACKGROUND/OBJECTIVE: Despite the high efficacy of using Continuous positive airway pressure (CPAP) in reversing upper airway obstruction in obstructive sleep apnea (OSA), the efficiency of this treatment is limited due to the low adherence. Mask pressure is suggested to play a significant role in adherence. In this study, we intend to investigate the effect of Lidocaine-prilocaine cream CPAP mask on pressure sensation.
In this study, 75 patients referred to CPAP titration were divided into three groups. In groups one and two, Lidocaine-prilocaine cream and Petroleum jelly were used respectively. The third group had no intervention.
VAS discomfort immediately (VAS0), after 15 min (VAS15), and the next day (VAS all) in three groups were compared. VAS0, VAS15, and VAS all were not significantly different among the three groups ( > 0.05). Among participants with VAS0 above 5, VAS15 was significantly lower in intervention groups than the control group ( < 0.05).
This study shows that both Petroleum jelly and Lidocaine-prilocaine cream can be used for decreasing pressure sensation during CPAP titration among patients who suffer excessive facial discomfort immediately after putting on a CPAP mask.
背景/目的：尽管持续气道正压通气（CPAP）在逆转阻塞性睡眠呼吸暂停（OSA）上气道阻塞方面疗效显著，但由于依从性低，该治疗的效果受到限制。面罩压力被认为在依从性方面起着重要作用。在本研究中，我们旨在探讨利多卡因-丙胺卡因乳膏CPAP面罩对压力感觉的影响。
在本研究中，75名接受CPAP滴定的患者被分为三组。第一组和第二组分别使用利多卡因-丙胺卡因乳膏和凡士林。第三组不进行干预。
比较三组患者即刻（VAS0）、15分钟后（VAS15）和次日（VAS全部）的视觉模拟评分法不适感。三组之间的VAS0、VAS15和VAS全部无显著差异（>0.05）。在VAS0高于5的参与者中，干预组的VAS15显著低于对照组（<0.05）。
本研究表明，对于佩戴CPAP面罩后立即出现过度面部不适的患者，凡士林和利多卡因-丙胺卡因乳膏均可用于减轻CPAP滴定期间的压力感觉。
