一个先有鸡还是先有蛋的困境：恶性高血压与人类免疫缺陷病毒诱导的血栓性微血管病性贫血难题。

A Chicken-and-Egg Predicament: Malignant Hypertension Versus HIV-Induced Thrombotic Microangiopathic Anemia Conundrum.

作者信息

Zamanian Daniel, Agrawal Akshat, Pawa Arpita, Brunet-Rodriguez Hector J, Alla Sreedhara

机构信息

Internal Medicine, Willis Knighton Healthcare System, Shreveport, USA.

Internal Medicine, Pt. Jawahar Lal Nehru Memorial Medical College, Raipur, IND.

出版信息

Cureus. 2024 Jul 11;16(7):e64304. doi: 10.7759/cureus.64304. eCollection 2024 Jul.

DOI:10.7759/cureus.64304

PMID:39130838

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11316243/

Abstract

Thrombotic microangiopathy (TMA) is a condition characterized by hemolytic anemia, thrombocytopenia, and organ damage due to the formation of microthrombi. It can be classified as primary or secondary, with secondary TMA being associated with conditions such as infections, autoimmune diseases, and malignancies. This report details the case of a 39-year-old male with secondary TMA, exploring the potential roles of malignant hypertension and HIV infection with the aim of examining the potential link between malignant hypertension and HIV infection in the development of TMA, highlighting the need for a thorough and broad diagnostic approach.

摘要

血栓性微血管病（TMA）是一种以溶血性贫血、血小板减少以及因微血栓形成导致器官损害为特征的病症。它可分为原发性或继发性，继发性TMA与感染、自身免疫性疾病和恶性肿瘤等病症相关。本报告详细介绍了一名患有继发性TMA的39岁男性病例，探讨恶性高血压和HIV感染的潜在作用，旨在研究恶性高血压与HIV感染在TMA发生发展过程中的潜在联系，强调需要采取全面且广泛的诊断方法。