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心肌梗死后左心室游离壁破裂的保守治疗

Post-Myocardial Infarction (MI) Left Ventricular Free Wall Rupture Managed Conservatively.

作者信息

Malik Nikhale, Vadher Abhishek, Panikottu Kurian, Kambhatla Sujata, Harder William

机构信息

Internal Medicine, Garden City Hospital, Garden City, USA.

Cardiology, Garden City Hospital, Garden City, USA.

出版信息

Cureus. 2024 Jul 12;16(7):e64395. doi: 10.7759/cureus.64395. eCollection 2024 Jul.

Abstract

Left ventricular free wall rupture (LVFWR) is an uncommon but often fatal complication of acute myocardial infarction. LVFWR is managed with hemodynamic stabilization and is typically followed by surgical intervention with varying approaches depending on the type of LVFWR. A 78-year-old male with a history of coronary artery bypass graft (CABG) was admitted with ST-segment elevation myocardial infarction. Left heart catheterization showed complete occlusion of the saphenous vein graft to the 1st obtuse marginal artery. The patient was not a candidate for percutaneous coronary intervention or CABG. The patient later developed atrial fibrillation with a rapid ventricular response which was managed with beta blockers. Computed tomography pulmonary angiogram was done to rule out pulmonary embolus; however, it demonstrated findings of a lateral LVFWR. The patient was deemed a poor surgical candidate for cardiothoracic surgery, and the LVFWR was managed conservatively with metoprolol succinate and bed rest. He later required amiodarone and direct current cardioversion due to the recurrence of atrial fibrillation. Two months following the LVFWR, the patient remained stable with no apparent complications. In a certain subset of LVFWR patients, surgical management may not be possible given patient anatomy and other high-risk factors. In these cases, conservative management with bed rest and beta blockers and treatment of ventricular and atrial arrhythmias may be a viable therapeutic option.

摘要

左心室游离壁破裂(LVFWR)是急性心肌梗死一种少见但常致命的并发症。LVFWR的治疗需血流动力学稳定,通常随后根据LVFWR的类型采用不同方法进行手术干预。一名有冠状动脉旁路移植术(CABG)病史的78岁男性因ST段抬高型心肌梗死入院。左心导管检查显示隐静脉移植血管至第一钝缘支动脉完全闭塞。该患者不适合进行经皮冠状动脉介入治疗或CABG。患者后来出现房颤伴快速心室反应,使用β受体阻滞剂进行治疗。进行了计算机断层扫描肺动脉造影以排除肺栓塞;然而,检查结果显示存在左心室游离壁外侧破裂。该患者被认为是心胸外科手术的不良候选者,LVFWR采用琥珀酸美托洛尔和卧床休息进行保守治疗。他后来因房颤复发需要使用胺碘酮和直流电复律。LVFWR发生两个月后,患者情况稳定,无明显并发症。在某些LVFWR患者亚组中,鉴于患者解剖结构和其他高危因素,可能无法进行手术治疗。在这些情况下,卧床休息和使用β受体阻滞剂进行保守治疗以及治疗室性和房性心律失常可能是一种可行的治疗选择。

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