口服酒精对志愿者胃肠胰激素的影响。
The effect of oral alcohol on gastroenteropancreatic hormones in volunteers.
作者信息
Dinsmore W W, Callender M E, McMaster D, Love A H, Buchanan K D
出版信息
Ulster Med J. 1985 Oct;54(2):185-90.
This study has examined changes in gastrointestinal hormones induced by alcohol. Ten normal volunteers consumed an orange and carbohydrate-containing drink on two separate occasions, with and without 50g alcohol. There was a significant hyperglycaemia associated with alcohol ingestion but no difference was noted in insulin or gastric inhibitory polypeptide in the two groups. Gastrin release was stimulated by alcohol but pancreatic polypeptide release and N-terminal glucagon release were both suppressed by alcohol. There was no difference in release of secretin or C-terminal glucagon in either group.
本研究检测了酒精引起的胃肠激素变化。10名正常志愿者在两个不同场合饮用了含橙子和碳水化合物的饮料，一次含50克酒精，一次不含酒精。酒精摄入会导致显著的高血糖，但两组的胰岛素或胃抑制性多肽没有差异。酒精刺激胃泌素释放，但酒精抑制胰多肽释放和N端胰高血糖素释放。两组的促胰液素或C端胰高血糖素释放没有差异。
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