Prasad Sonal, Xiong Jay, Embry Edsel, Abdelghani Loui
Department of Internal Medicine, St. Joseph's Medical Center, Stockton, USA.
Department of Pulmonary and Critical Care Medicine, St. Joseph's Medical Center, Stockton, USA.
Cureus. 2024 Jul 11;16(7):e64367. doi: 10.7759/cureus.64367. eCollection 2024 Jul.
Antiphospholipid syndrome (APS) is characterized by thrombosis in any organ or tissue, accompanied by the presence of antiphospholipid antibodies. Although rare, APS can progress to catastrophic APS (CAPS), a life-threatening complication involving the development of multi-organ thromboses. The mortality rate is high. Treatment consists of triple therapy with anticoagulation, glucocorticoids, and therapeutic plasmapheresis or intravenous immunoglobulins. We present a case of a patient with CAPS, requiring a multidisciplinary team approach to help diagnose and treat this complex disease.
抗磷脂综合征（APS）的特征是任何器官或组织发生血栓形成，并伴有抗磷脂抗体的存在。尽管罕见，但APS可进展为灾难性抗磷脂综合征（CAPS），这是一种危及生命的并发症，涉及多器官血栓形成。死亡率很高。治疗包括抗凝、糖皮质激素以及治疗性血浆置换或静脉注射免疫球蛋白的三联疗法。我们报告一例CAPS患者，需要多学科团队方法来帮助诊断和治疗这种复杂疾病。
