一例因持续性腹泻和腹痛诊断为免疫球蛋白G4相关性胃肠病的病例
A Case of Immunoglobulin G4-Related Gastrointestinal Disease Diagnosed From Persistent Diarrhea and Abdominal Pain.
作者信息
Hirano Takehiro, Kawakami Yujiro, Nakabayashi Sayaka, Wagatsuma Kohei, Ishigami Keisuke, Masaki Yoshiharu, Murota Ayako, Kanda Masatoshi, Sugita Shintaro, Notohara Kenji, Nakase Hiroshi
机构信息
Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.
Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.
出版信息
Gastro Hep Adv. 2023 Jul 21;2(8):1089-1092. doi: 10.1016/j.gastha.2023.07.009. eCollection 2023.
Immunoglobulin G4-related disease (IgG4-RD) is a systemic inflammatory disease characterized by the infiltration of IgG4-positive plasma cells and fibrosis in organs throughout the body. IgG4-RD involvement in the gastrointestinal (GI) tract (IgG4-related GI disease; IgG4-GID) is rare, and the disease concept remains unclear. Generally, IgG4-GID has been reported with morphological changes, including ulcers, strictures, and submucosal tumors. Here, we report a case of IgG4-GID with persistent diarrhea and abdominal pain in which typical endoscopic findings were absent. This case suggests the unidentified clinical features of IgG4-GID.
免疫球蛋白G4相关性疾病（IgG4-RD）是一种全身性炎症性疾病，其特征是IgG4阳性浆细胞浸润和全身各器官纤维化。IgG4-RD累及胃肠道（IgG4相关性胃肠道疾病；IgG4-GID）较为罕见，疾病概念仍不明确。一般来说，IgG4-GID有形态学改变的报道，包括溃疡、狭窄和黏膜下肿瘤。在此，我们报告一例伴有持续性腹泻和腹痛的IgG4-GID病例，该病例无典型的内镜检查结果。该病例提示了IgG4-GID存在尚未明确的临床特征。
Zotero 插件