Pongsuwun Kewalin, Puwarawuttipanit Wimolrat, Nguantad Sunisa, Samart Benjakarn, Saikaew Khalinee, Ruksakulpiwat Suebsarn
Department of Medical Nursing, Faculty of Nursing, Mahidol University, Bangkok, Thailand.
Department of Nursing Siriraj Hospital, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
J Multidiscip Healthc. 2024 Aug 6;17:3791-3802. doi: 10.2147/JMDH.S477873. eCollection 2024.
There remains a gap in understanding post-sepsis outcomes, particularly regarding the factors that influence the quality of life (QOL) among sepsis survivors during and after hospitalization.
To determine factors impacting QOL among sepsis survivors during and after hospitalization based on the evaluation and synthesis of current evidence.
This review encompassed studies published from January 2020 to December 2024, sourced from Scopus, PubMed, Medline, ScienceDirect, CINAHL Plus with Full Text, and Web of Science. The process of identifying, screening, excluding, and including articles followed the guidelines set by the Preferred Reporting Items for Systematic Reviews (PRISMA). Data synthesis for theme generation was conducted using the convergent integrated analysis framework as recommended by the Joanna Briggs Institute.
A total of 1164 records were identified from the databases. After removing 130 duplicates, 1034 articles remained for screening based on their titles and abstracts according to the inclusion and exclusion criteria. At this stage, 1021 articles did not meet the criteria and were excluded, leaving 13 articles eligible for full-text screening. During this phase, 5 articles were excluded for various reasons, resulting in eight studies being included in the systematic review. Data synthesis of these studies revealed seven themes related to factors impacting QOL among sepsis survivors during and after hospitalization: 1) Physical Health Dimension, 2) Mental Health Dimension, 3) Treatment During Hospitalization, 4) Spiritual Dimension, 5) Social Support, 6) Mortality, and 7) Blood Biomarkers.
This systematic review provides valuable insights into the factors affecting the quality of life among sepsis survivors during and after hospitalization. These findings enhance the current knowledge base and offer clinicians, researchers, and policymakers actionable insights to improve outcomes and well-being for sepsis survivors.
在理解脓毒症后结局方面仍存在差距，尤其是关于影响脓毒症幸存者在住院期间及出院后生活质量（QOL）的因素。
基于对现有证据的评估和综合，确定影响脓毒症幸存者在住院期间及出院后生活质量的因素。
本综述涵盖了2020年1月至2024年12月发表的研究，这些研究来源于Scopus、PubMed、Medline、ScienceDirect、CINAHL Plus with Full Text和Web of Science。文章的识别、筛选、排除和纳入过程遵循系统评价的首选报告项目（PRISMA）所设定的指南。使用乔安娜·布里格斯研究所推荐的收敛性综合分析框架进行主题生成的数据综合。
从数据库中总共识别出1164条记录。去除130条重复记录后，根据纳入和排除标准，剩余1034篇文章基于标题和摘要进行筛选。在此阶段，1021篇文章不符合标准被排除，剩下13篇文章符合全文筛选条件。在此阶段，5篇文章因各种原因被排除，最终8项研究被纳入系统评价。这些研究的数据综合揭示了与影响脓毒症幸存者在住院期间及出院后生活质量的因素相关的七个主题：1）身体健康维度，2）心理健康维度，3）住院期间的治疗，4）精神维度，5）社会支持，6）死亡率，7）血液生物标志物。
本系统评价为影响脓毒症幸存者在住院期间及出院后生活质量的因素提供了有价值的见解。这些发现增强了当前的知识库，并为临床医生、研究人员和政策制定者提供了可采取行动的见解，以改善脓毒症幸存者的结局和福祉。
