Virgen-Carrillo Luis R, Díaz-Sandoval Larry, Rossi Maximiliano, Pedernera Gustavo O, Duarte Ernesto R, Pascua Julio A, Lugo-Gavidia Leslie M, Lamelas Pablo
Department of Interventional Cardiology, Virgen Cardiovascular Research, Guadalajara, Mexico.
Department of Interventional Cardiology, Universidad Autonóma de Guadalajara, Guadalajara, Mexico.
J Soc Cardiovasc Angiogr Interv. 2024 Apr 4;3(7):101931. doi: 10.1016/j.jscai.2024.101931. eCollection 2024 Jul.
Chronic limb-threatening ischemia (CLTI) represents the most advanced stage of lower extremity peripheral artery disease (PAD). The aim of this manuscript is to provide an overview of the demographic and clinical characteristics of patients with lower-limb peripheral artery disease, as well as the procedural and technical aspects of peripheral endovascular interventions in Latin-America.
The SOLACI peripheral registry is a prospective, multi-center, observational, and hospital-based registry of patients with lower-limb PAD, who are treated with endovascular interventions across Latin American countries.
A total of 1057 independent procedures (997 patients) were analyzed in this report. The most common clinical presentation was CLTI (61.2%): Advanced stage of the disease was common, and the symptomatic classification was predominately Rutherford V (minor tissue loss) in 37.6%. Index endovascular procedures mainly treated femoral-popliteal and infrapopliteal regions. Disease extending across multiple vascular territories was common and 27.6% of patients underwent angioplasty of multiple regions during the same procedure. There was a high prevalence of cardiovascular risk factors and concomitant comorbidities: hypertension (84.5%), dyslipidemia 67.4%), diabetes mellitus (64.7%), myocardial infarction (17%) and stroke (8.4%). Major adverse events during hospitalization included death from any cause (1.3%), cardiovascular death (0.7 %), myocardial infarction (0.4%), stroke (0.1%) and bleeding (0.8%).
Real-world data on lower limb-PAD in Latin American countries will help us identify unmet needs and generate evidence-based recommendations to facilitate the development of more effective preventive and treatment strategies according to each country's necessities and resources.
慢性肢体威胁性缺血（CLTI）是下肢外周动脉疾病（PAD）的最严重阶段。本文旨在概述下肢外周动脉疾病患者的人口统计学和临床特征，以及拉丁美洲外周血管腔内介入治疗的操作和技术方面。
SOLACI外周登记系统是一个前瞻性、多中心、观察性且基于医院的登记系统，登记的是拉丁美洲国家接受血管腔内介入治疗的下肢PAD患者。
本报告共分析了1057例独立手术（997例患者）。最常见的临床表现是CLTI（61.2%）：疾病晚期很常见，症状分类主要为卢瑟福V级（轻度组织缺损），占37.6%。首次血管腔内手术主要治疗股腘动脉和腘以下区域。疾病累及多个血管区域很常见，27.6%的患者在同一次手术中接受了多个区域的血管成形术。心血管危险因素和合并症的患病率很高：高血压（84.5%）、血脂异常（67.4%）、糖尿病（64.7%）、心肌梗死（17%）和中风（8.4%）。住院期间的主要不良事件包括任何原因导致的死亡（1.3%）、心血管死亡（0.7%）、心肌梗死（0.4%）、中风（0.1%）和出血（0.8%）。
拉丁美洲国家下肢PAD的真实世界数据将有助于我们识别未满足的需求，并生成基于证据的建议，以便根据每个国家的需求和资源制定更有效的预防和治疗策略。
