Suppr超能文献

桥本病伪装为急性肾小管损伤和横纹肌溶解症。

Hashimoto's thyroiditis masquerading as acute tubular injury and rhabdomyolysis.

机构信息

SRM Medical College Hospital and Research Centre, Department of Nephrology, Chengalpattu, India.

出版信息

J Bras Nefrol. 2024 Jul-Sep;46(3):e20240022. doi: 10.1590/2175-8239-JBN-2024-0022en.

Abstract

Hashimoto's thyroiditis manifesting as hypothyroidism has been implicated in glomerular disorders due to autoantibody formation. Here we present the case of a 26-year-old male without any comorbidities presenting with easy fatiguability and weight gain for 2 months. He was found to have a creatinine of 2.1 mg/dL with a history of rhinitis treated with anti-histaminic three days prior to the hospital visit. He had symptoms of intermittent myalgia for the past two weeks. On laboratory evaluation, he was found to have raised CPK, elevated TSH, low normal T4, and positive anti-TPO and anti-Tg antibodies. Neck ultrasound revealed linear echogenic septations in the thyroid gland. Renal biopsy revealed acute tubular injury. Appropriate thyroxine supplementation was started and his creatinine decreased to 1.2 mg/dL after 1 month. It is important that clinicians should be aware of this rare kidney presentation in Hashimoto's thyroiditis.

摘要

桥本甲状腺炎引起的甲状腺功能减退症可因自身抗体的形成而导致肾小球疾病。我们在此报告一例 26 岁男性病例,无任何合并症,表现为易疲劳和体重增加 2 个月。他在就诊前三天因鼻炎接受抗组胺治疗,发现肌酐为 2.1mg/dL。过去两周他有间歇性肌肉疼痛的症状。实验室检查发现肌酸激酶升高,促甲状腺激素升高,甲状腺素正常低值,抗甲状腺过氧化物酶抗体和抗甲状腺球蛋白抗体阳性。颈部超声显示甲状腺线性强回声分隔。肾活检显示急性肾小管损伤。开始适当补充甲状腺素,1 个月后肌酐降至 1.2mg/dL。重要的是,临床医生应该意识到桥本甲状腺炎的这种罕见肾脏表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d179/11318353/a9bcea594cfa/2175-8239-jbn-46-3-e20240022-gf01.jpg

相似文献

本文引用的文献

3
Autoimmune Thyroiditis and Glomerulopathies.自身免疫性甲状腺炎与肾小球病
Front Endocrinol (Lausanne). 2017 Jun 2;8:119. doi: 10.3389/fendo.2017.00119. eCollection 2017.
4
Diagnostic evaluation of rhabdomyolysis.横纹肌溶解症的诊断评估。
Muscle Nerve. 2015 Jun;51(6):793-810. doi: 10.1002/mus.24606. Epub 2015 Mar 14.
6
Thyroid hormones and skeletal muscle--new insights and potential implications.甲状腺激素与骨骼肌:新的认识与潜在影响
Nat Rev Endocrinol. 2014 Apr;10(4):206-14. doi: 10.1038/nrendo.2013.238. Epub 2013 Dec 10.
7
Interactions between thyroid disorders and kidney disease.甲状腺疾病与肾脏疾病之间的相互作用。
Indian J Endocrinol Metab. 2012 Mar;16(2):204-13. doi: 10.4103/2230-8210.93737.
8
Hypothyroidism and associated acute renal failure.甲状腺功能减退症与相关急性肾衰竭。
J R Soc Med. 2009 May;102(5):199-200. doi: 10.1258/jrsm.2008.080302.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验