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造血干细胞移植后血栓性微血管病:一例酷似 Purtscher 样视网膜病变。

Thrombotic Microangiopathy Following Hematopoietic Stem Cell Transplantation: A Case of Purtscher-like Retinopathy.

出版信息

Ophthalmic Surg Lasers Imaging Retina. 2024 Oct;55(10):603-606. doi: 10.3928/23258160-20240528-05. Epub 2024 Aug 1.

Abstract

Purtscher-like retinopathy (PLR) is a rare entity related with retinal ischemia due to endothelial dysfunction and embolization. We present a case of a 17-year-old patient who presented with PLR associated with transplant-associated thrombotic microangiopathy. Visual acuity was finger counting at 1 meter in both eyes. Fundoscopy demonstrated peripapillary cotton-wool spots and hypopigmentation in the middle peripheral retina. Both eyes showed signs of macular edema with intraretinal hemorrhages. Optical coherence tomography and fundus fluorescence angiography was performed to support the diagnosis. After systemic treatments and panretinal photocoagulation, the patient's vision improved and the macular edema resolved. .

摘要

普勒歇尔样视网膜病变(PLR)是一种罕见的疾病,与视网膜缺血有关,其病因是内皮功能障碍和栓塞。我们报告了一例 17 岁患者,其患有与移植相关的血栓性微血管病相关的普勒歇尔样视网膜病变。该患者双眼视力在 1 米处仅能指数辨认。眼底镜检查显示视盘周围棉絮斑和中周部视网膜色素脱失。双眼均有黄斑水肿合并视网膜内出血。行光学相干断层扫描和眼底荧光血管造影以支持诊断。经全身治疗和全视网膜光凝治疗后,患者视力改善,黄斑水肿消退。

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