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首例北美使用柏林心脏 EXCOR 主动泵驱动的经验。

First North American experience with the Berlin Heart EXCOR Active driver.

机构信息

Department of Pediatric Cardiology, University of Alberta, Edmonton, Alberta, Canada; Division of Pediatric Cardiology, Stollery Children's Hospital, Edmonton, Alberta, Canada.

Division of Pediatric Cardiology, Stollery Children's Hospital, Edmonton, Alberta, Canada.

出版信息

J Heart Lung Transplant. 2024 Nov;43(11):1861-1863. doi: 10.1016/j.healun.2024.08.005. Epub 2024 Aug 10.

Abstract

For smaller pediatric patients on ventricular assist devices, the Berlin Heart EXCOR remains the main form of durable support. It requires a connection to the external IKUS, which has limited portability and battery life. The new EXCOR Active mobile driving unit has a battery life of up to 13 hours. We describe the first North American experience with the EXCOR Active in pediatric patients with a Berlin Heart device. A retrospective chart review was undertaken. Between October 2022 and March 2024, 7 patients were on a Berlin Heart and supported with the EXCOR Active. All patients were initially supported with the IKUS with a median time to transition to the EXCOR Active of 12.0 days (interquartile range [IQR] 9.5, 18.5) and a median time of support with the EXCOR Active of 65.0 days (IQR, 32.0, 81.0). The EXCOR Active posed no significant safety issues, and minimal operating issues were noted. Following the transition from IKUS to the EXCOR Active, there was increased patient and caregiver mobility throughout the hospital. Use of the EXCOR Active has the potential to improve the quality of life in pediatric patients waiting for heart transplantation.

摘要

对于使用心室辅助设备的小型儿科患者,Berlin Heart EXCOR 仍然是主要的持久支持形式。它需要与外部的 IKUS 连接,而 IKUS 的便携性和电池寿命有限。新型 EXCOR Active 移动驱动单元的电池寿命最长可达 13 小时。我们描述了在使用 Berlin Heart 设备的儿科患者中首次使用 EXCOR Active 的北美经验。进行了回顾性图表审查。在 2022 年 10 月至 2024 年 3 月期间,有 7 名患者使用 Berlin Heart 并接受了 EXCOR Active 的支持。所有患者最初均通过 IKUS 进行支持,从过渡到 EXCOR Active 的中位时间为 12.0 天(四分位距 [IQR] 9.5,18.5),使用 EXCOR Active 的中位时间为 65.0 天(IQR,32.0,81.0)。EXCOR Active 没有带来重大安全问题,仅注意到一些轻微的操作问题。从 IKUS 过渡到 EXCOR Active 后,患者和照顾者在整个医院的移动性得到了提高。使用 EXCOR Active 有可能提高等待心脏移植的儿科患者的生活质量。

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