Varghese Nibu, K D Vimal Chandraghosh, Menon Deepak, P Abdurahiman, Kattadimmal Anoop, Mathew Jubin, B S Shobika, Babu Nyla Mary
Department of Neurology, KMCT Medical college, Mukkam, Mukkam, Kozhikode, 673602, India.
Neurology, Southern Illinois University, Springfield, United States of America.
Acta Neurol Belg. 2024 Dec;124(6):2029-2033. doi: 10.1007/s13760-024-02617-7. Epub 2024 Aug 13.
Dropped head syndrome (DHS) is characterized by a passively correctable chin-on-neck deformity inerect posture and can stem from a wide variety of neurological disorders spanning the neuraxis. Neuromuscular disorders account for a major chunk of DHS and include disease of anterior horn celldiseases, polyradiculopathies and cervical plexopathies, disease of neuromuscular junction andmyopathies. Isolated DHS without additional neurological features poses a management challenge, particularly because the symptoms can signifi cantly impact the patient's quality of life and may notalways respond to treatment..(Ref)Here we present a patient with isolated DHS with evaluation revealingisolated next extensor myopathy with remarkable response to treatment. Although isolated neckextensor myopathy typically exhibit poor immunomodulatory response, timely identifi cation and earlyintervention probably can lead to a favourable outcome in a subgroup of patients.
低头综合征(DHS)的特征是在直立姿势下出现可被动纠正的颈前畸形,其可源于神经系统轴内的多种神经疾病。神经肌肉疾病占DHS的很大一部分,包括前角细胞疾病、多神经根病和颈丛病、神经肌肉接头疾病和肌病。无其他神经特征的孤立性DHS带来了管理挑战,特别是因为这些症状会显著影响患者的生活质量,且可能对治疗无反应。(参考文献)在此,我们报告一例孤立性DHS患者,评估显示为孤立性颈伸肌肌病,对治疗反应显著。虽然孤立性颈伸肌肌病通常表现出较差的免疫调节反应,但及时识别和早期干预可能会使一部分患者获得良好的治疗结果。