Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Akdeniz University, Antalya, Turkey.
Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Yuzuncu Yil University, Van, Turkey.
Clin Oral Investig. 2024 Aug 13;28(9):483. doi: 10.1007/s00784-024-05872-3.
The aim of this study was to compare leukocyte and platelet-rich fibrin (L-PRF) and photobiomodulation (PBM) applications, which have been repeatedly reported to be superior to control groups, in terms of pain, soft tissue and bone healing in tooth extraction sockets.
This double-blind, randomized clinical study was completed with 34 patients, who had an indication for extraction of their bilaterally impacted teeth. The right and left teeth of the patients were randomly divided into L-PRF and PBM groups. L-PRF group was treated with the blood product centrifuged for 12 min at 2700 rpm, and the PBM group was treated with a diode laser at different points for 60 s with a wavelength of 940 nm in repeated sessions. Postoperative pain was evaluated using Visual Analogue Scale (VAS), soft tissue healing with Landry Index (LI), tissue healing in the distal region of mandibular second molar by probing depth measurement, and bone healing via panoramic x-ray using the Image J program.
No statistically significant difference was found for any variable compared between the groups.
L-PRF and PBM applications provide similar support in the healing of extraction sockets. Nevertheless, the advantages and disadvantages of both methods determine their usage areas.
While L-PRF is advantageous in the early healing of extraction sockets, PBM may be preferred in terms of bone trabeculation in the long term.
本研究旨在比较富白细胞和血小板纤维蛋白(L-PRF)与光生物调节(PBM)的应用,这两种方法已被多次报道在拔牙窝的疼痛、软组织和骨愈合方面优于对照组。
本双盲、随机临床试验共纳入 34 名双侧埋伏牙患者。患者的左右牙齿随机分为 L-PRF 组和 PBM 组。L-PRF 组采用 2700rpm 离心 12 分钟的血液制品进行治疗,PBM 组采用波长为 940nm 的二极管激光在不同点进行 60 秒的重复治疗。术后疼痛采用视觉模拟评分(VAS)评估,软组织愈合采用 Landry 指数(LI)评估,下颌第二磨牙远中部位的组织愈合采用探测深度测量评估,骨愈合采用 Image J 程序的全景 X 光评估。
组间比较,各变量均无统计学差异。
L-PRF 和 PBM 的应用在拔牙窝的愈合中提供了相似的支持。然而,两种方法的优缺点决定了它们的使用领域。
虽然 L-PRF 在拔牙窝的早期愈合方面具有优势,但 PBM 可能在长期的骨小梁形成方面更具优势。