Takeuchi T, Kawakita S
Jpn Circ J. 1985 Dec;49(12):1254-7. doi: 10.1253/jcj.49.1254.
Studies on the prevalence of beta-hemolytic streptococci in throats among primary school children were performed in Otsu City. In the first study, evidence of streptococcal infections was investigated in 41373 children of first grade of all primary schools for the 13 years from 1970 to 1982. An average of 12.2% of the strains isolated belonged to group A. The order of frequency of the other Groups was B, C and G respectively. The most predominant type of Group A streptococci was Type 12. In the second study, evidence of streptococcal infections was investigated in 87 children of the first grade of one primary school for the 5 years from 1977 to 1982. Throat cultures were repeated four times a year during the period of five years. Entire negative throat cultures over a 5-year period were observed in only 4 children. The prevalence of beta-hemolytic streptococci and Group A streptococci in throats were higher than those observed in the first study. The predominant types of Group A were Types 1, 6 and 28, although the relative predominance of these Types varied at different times during 5 years. High serum ASO titers were observed in the children who harbored Type 6 strains of Group A streptococci in throats. In 5 children Group A streptococci were frequently recovered from throats during the study period, and the same type of strains of Group A streptococci were isolated repeatedly.
在大津市开展了关于小学生咽喉中β溶血性链球菌流行情况的研究。在第一项研究中，于1970年至1982年的13年间，对所有小学一年级的41373名儿童进行了链球菌感染证据的调查。分离出的菌株中平均有12.2%属于A组。其他组的频率顺序分别为B组、C组和G组。A组链球菌最主要的类型是12型。在第二项研究中，于1977年至1982年的5年间，对一所小学一年级的87名儿童进行了链球菌感染证据的调查。在这5年期间，每年重复进行4次咽喉培养。仅4名儿童在5年期间咽喉培养结果全部为阴性。咽喉中β溶血性链球菌和A组链球菌的流行率高于第一项研究中的观察结果。A组的主要类型是1型、6型和28型，尽管在5年期间不同时间这些类型的相对优势有所变化。咽喉中携带A组链球菌6型菌株的儿童血清抗链球菌溶血素O滴度较高。在5名儿童中，在研究期间咽喉中频繁检出A组链球菌，并且反复分离出同一类型的A组链球菌菌株。
