Baltrak Yusuf Atakan, Akdoğan Nebil, Değer Mutlu, Izol Volkan, Aridoğan Ibrahim Atilla, Satar Nihat
Division Pediatric Urology, Department of Urology, Medical Faculty, Cukurova University, Adana, Turkey.
Asian J Urol. 2024 Jul;11(3):437-442. doi: 10.1016/j.ajur.2023.05.007. Epub 2023 Dec 9.
Vesicoureteral reflux (VUR) index is a simple, validated tool that reliably predicts significant improvement and spontaneous resolution of primary reflux in children. The aim of this study was to evaluate and compare the ureter diameter ratio (UDR) and VUR index (VURx) of patients treated with endoscopic injection (EI) and ureteroneocystostomy (UNC) methods in the pediatric age group due to primary VUR.
Patients under the age of 18 years old who underwent EI and UNC with the diagnosis of primary VUR between January 2011 and September 2021 were determined as the participants. The UDR was assessed using voiding cystourethrography, and the VURx score was determined prior to treatment based on hospital records included in the study.
A total of 255 patients, 60 (23.5%) boys and 195 (76.5%) girls, with a mean age of 76.5 (range 13.0-204.0) months, were included in the study. EI was applied to 130 (51.0%) patients and UNC was applied to 125 (49.0%) patients due to primary VUR. The optimum cut-off for the distal UDR was obtained as 0.17 with sensitivity and specificity of 73.0% and 63.0%, respectively. The positive and negative predictive values were 66.0% and 70.0%, respectively.
When the UDR and VURx score are evaluated together for the surgical treatment of primary VUR in the pediatric age group, it is thought that it may be useful in predicting the clinical course of the disease and evaluating surgical treatment options.
膀胱输尿管反流(VUR)指数是一种简单且经过验证的工具,可可靠地预测儿童原发性反流的显著改善和自发缓解情况。本研究的目的是评估和比较因原发性VUR在儿科年龄组中接受内镜注射(EI)和输尿管膀胱再植术(UNC)治疗的患者的输尿管直径比(UDR)和VUR指数(VURx)。
将2011年1月至2021年9月期间因原发性VUR接受EI和UNC治疗且年龄在18岁以下的患者确定为研究参与者。使用排尿性膀胱尿道造影评估UDR,并根据研究中纳入的医院记录在治疗前确定VURx评分。
本研究共纳入255例患者,其中男孩60例(23.5%),女孩195例(76.5%),平均年龄76.5(范围13.0 - 204.0)个月。因原发性VUR,130例(51.0%)患者接受了EI治疗,125例(49.0%)患者接受了UNC治疗。远端UDR的最佳截断值为0.17,敏感性和特异性分别为73.0%和63.0%。阳性和阴性预测值分别为66.0%和70.0%。
在评估儿科年龄组原发性VUR的手术治疗时,若同时评估UDR和VURx评分,可能有助于预测疾病的临床进程并评估手术治疗方案。