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纤维蛋白原浓缩物在需要经导管动脉栓塞术的小儿脾损伤中的有效应用。

Effective use of fibrinogen concentrate in a pediatric splenic injury requiring transcatheter arterial embolization.

作者信息

Ando Sho, Dote Hisashi, Okuma Seigo, Atsumi Takahiro

机构信息

Department of Emergency & Critical Care Medicine, Seirei Hamamatsu General Hospital, 2-12-12 Sumiyoshi, Chuo-Ku, Hamamatsu, Shizuoka 430-8558, Japan.

出版信息

Trauma Case Rep. 2024 Jul 15;53:101076. doi: 10.1016/j.tcr.2024.101076. eCollection 2024 Oct.

Abstract

Correction of coagulation is a crucial aspect of trauma care. While there are reports highlighting the effectiveness of fibrinogen concentrate in severe trauma cases with coagulopathic complications, literature on its use in pediatric cases remains limited. This paper discusses the case of a 5-year-old male presenting with a splenic injury and associated coagulopathy. We administered fibrinogen concentrate to enhance his coagulability prior to performing transcatheter arterial embolization utilizing gelatin sponges, aiming for optimal hemostasis. Post-administration, the patient's fibrinogen levels improved significantly, leading to successful hemostasis and a positive clinical outcome.

摘要

纠正凝血功能是创伤治疗的一个关键方面。虽然有报告强调纤维蛋白原浓缩物在伴有凝血病并发症的严重创伤病例中的有效性,但关于其在儿科病例中的应用的文献仍然有限。本文讨论了一名5岁男性因脾损伤及相关凝血病就诊的病例。在使用明胶海绵进行经导管动脉栓塞之前,我们给予纤维蛋白原浓缩物以增强其凝血能力,旨在实现最佳止血效果。给药后,患者的纤维蛋白原水平显著改善,实现了成功止血并取得了良好的临床结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b38/11321445/c79c7ff61a92/gr1.jpg

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