Mehta Anurag, Diwan Himanshi, Nathany Shrinidhi, Batra Ullas, Gupta Manoj, Panigrahi Manoj Kumar, Kumar Dushyant, Mattoo Sakshi, Singh Aayushi
Department of Laboratory Services and Molecular Diagnostics, Rajiv Gandhi Cancer Institute & Research Centre, Delhi, India.
Department of Medical Oncology, Rajiv Gandhi Cancer Institute & Research Centre, Delhi, India.
Clin Pathol. 2024 Aug 12;17:2632010X241269373. doi: 10.1177/2632010X241269373. eCollection 2024 Jan-Dec.
Advanced Non-Small Cell Lung Carcinoma (NSCLC) patients with gene rearrangement have shown significant therapeutic responses to tyrosine kinase inhibitors approved by the US Food and Drug Administration, with approximately 40 fusion partners documented in the existing literature. Our report highlights a novel fusion partner of that has demonstrated a conclusive response to the current standard of treatment.
具有基因重排的晚期非小细胞肺癌(NSCLC)患者对美国食品药品监督管理局批准的酪氨酸激酶抑制剂已显示出显著的治疗反应,现有文献中记录了约40种融合伴侣。我们的报告强调了一种新型融合伴侣,它已证明对当前的治疗标准有确切反应。