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阿那莫林诱发的极宽QRS波群心动过速。

An extremely wide QRS complex tachycardia induced by anamorelin.

作者信息

Shimojo Kazuki, Kanzaki Yasunori, Miyazawa Hiroyuki, Morishima Itsuro

机构信息

Department of Cardiology Ogaki Municipal Hospital Ogaki Japan.

出版信息

J Arrhythm. 2024 May 19;40(4):1022-1025. doi: 10.1002/joa3.13072. eCollection 2024 Aug.

Abstract

Anamorelin, a ghrelin receptor agonist, is used for cancer-related cachexia but can induce life-threatening arrhythmias. A case study illustrates an extremely wide QRS tachycardia, posing diagnostic challenges. Anamorelin cessation led to normalization, highlighting the importance of ECG monitoring, particularly in liver-compromised patients, and hemodynamic support are crucial during suspected toxicity.

摘要

阿那莫林是一种胃饥饿素受体激动剂,用于治疗癌症相关性恶病质,但可诱发危及生命的心律失常。一项病例研究显示了一种QRS波极宽的心动过速,带来了诊断挑战。停用阿那莫林后恢复正常,凸显了心电图监测的重要性,尤其是对肝功能受损的患者,而且在怀疑有药物毒性时血流动力学支持至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e75/11317694/a73162eb7188/JOA3-40-1022-g003.jpg

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