Shimojo Kazuki, Kanzaki Yasunori, Miyazawa Hiroyuki, Morishima Itsuro
Department of Cardiology Ogaki Municipal Hospital Ogaki Japan.
J Arrhythm. 2024 May 19;40(4):1022-1025. doi: 10.1002/joa3.13072. eCollection 2024 Aug.
Anamorelin, a ghrelin receptor agonist, is used for cancer-related cachexia but can induce life-threatening arrhythmias. A case study illustrates an extremely wide QRS tachycardia, posing diagnostic challenges. Anamorelin cessation led to normalization, highlighting the importance of ECG monitoring, particularly in liver-compromised patients, and hemodynamic support are crucial during suspected toxicity.
阿那莫林是一种胃饥饿素受体激动剂,用于治疗癌症相关性恶病质,但可诱发危及生命的心律失常。一项病例研究显示了一种QRS波极宽的心动过速,带来了诊断挑战。停用阿那莫林后恢复正常,凸显了心电图监测的重要性,尤其是对肝功能受损的患者,而且在怀疑有药物毒性时血流动力学支持至关重要。