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限制高龄男性使用辅助生殖技术——从北欧角度看利弊。

Limiting access to assisted reproductive technologies for males of advanced age-Pros and cons from a Nordic perspective.

机构信息

Fertility Department Sor, Telemark Hospital Trust, Porsgrunn, Norway.

Center for Fertility and Health, National Institute of Public Health, Oslo, Norway.

出版信息

Acta Obstet Gynecol Scand. 2024 Nov;103(11):2124-2129. doi: 10.1111/aogs.14944. Epub 2024 Aug 14.

Abstract

It is not controversial to state that parental age is increasing in several countries. But how to deal with this increase might be. Some Nordic countries have set an upper age limit for females seeking assisted reproduction in their national legislation, but none have done so for males. There are also recommendations in place that restrict access to publicly funded assisted reproduction for both females and males of advanced age in some Nordic countries. As recent data now show somatic and psychiatric health risks related to advanced paternal age, we ask if the time has come for countries to set an upper age limit for males seeking assisted reproduction like there already is for females, and summarize some of the risks and rewards involved in treating couples with advanced age in fertility clinics.

摘要

可以毫不夸张地说,在一些国家,父母的年龄正在增加。但如何应对这种增长可能是一个问题。一些北欧国家在国家立法中为寻求辅助生殖的女性设定了年龄上限,但没有为男性设定。一些北欧国家也有建议,限制高龄女性和男性获得公共资助的辅助生殖的机会。由于最近的数据显示,与高龄父亲相关的躯体和精神健康风险,我们不禁要问,是否到了为寻求辅助生殖的男性设定年龄上限的时候了,就像已经为女性设定的那样,并总结了在生育诊所中治疗高龄夫妇所涉及的一些风险和回报。

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本文引用的文献

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Fertility in the aging male: a systematic review.男性生育力随年龄增长而下降:系统综述。
Fertil Steril. 2022 Dec;118(6):1022-1034. doi: 10.1016/j.fertnstert.2022.10.035.
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Diagnosis and treatment of infertility in men: AUA/ASRM guideline part I.男性不育的诊断与治疗:AUA/ASRM 指南 第一部分。
Fertil Steril. 2021 Jan;115(1):54-61. doi: 10.1016/j.fertnstert.2020.11.015. Epub 2020 Dec 9.

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