Dapkekar Anil Balajirao, Satyanarayana Gedu
Department of Chemistry, Indian Institute of Technology Hyderabad (IITH), Kandi, Sangareddy, Telangana 502284, India.
Org Biomol Chem. 2024 Sep 11;22(35):7111-7116. doi: 10.1039/d4ob01137f.
Herein, we report a convenient and environmentally friendly electrochemical technique that enables the regioselective construction of 4-sulfenyl-1-isochromen-1-ones using readily available precursors such as -alkynyl benzoates and diaryl disulfides. This electrochemical process has been accomplished through constant current electrolysis in an undivided cell under external acid, catalyst, oxidant, or metal-free conditions. Owing to this protocol's mild reaction conditions, the products are obtained in good to very good yields, demonstrating a broad substrate scope and functional group tolerance.
在此，我们报道了一种便捷且环保的电化学技术，该技术能够使用诸如炔基苯甲酸酯和二芳基二硫化物等易得的前体，区域选择性地构建4-亚磺酰基-1-异色满-1-酮。这种电化学过程是通过在外部无酸、无催化剂、无氧化剂或无金属的条件下，在未分隔的电池中进行恒流电解来实现的。由于该方法的反应条件温和，产物的产率良好至非常好，展示了广泛的底物范围和官能团耐受性。
