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肾移植受者的诺卡菌感染——病例报告

Nocardial infection in a renal transplant recipient--a case report.

作者信息

Sack K, Schwieder G, Marre R, Hoyer J

出版信息

Scand J Urol Nephrol Suppl. 1985;92:59-66.

PMID:3914063
Abstract

Report is given about a 50 year old renal transplant recipient who developed signs of a severe pneumonia 37 days post transplantation. The diagnosis following chest X-ray and physical examination was multifocal nodular pneumonia of unknown origin in an immunosuppressed patient. Although a varying antibiotic chemotherapy was administered at high doses he died 4 weeks later without identification of the infective agent. Post-mortem and microbiological examinations revealed a systemic suppurative infection caused by Nocardia asteroides. Percutaneous or open lung biopsy within the first 10 days after onset of clinical symptoms has to be recommended to secure the diagnosis and treatment with sulphonamides.

摘要

报告了一名50岁的肾移植受者,其在移植后37天出现严重肺炎的症状。胸部X光检查和体格检查后的诊断为免疫抑制患者不明原因的多灶性结节性肺炎。尽管给予了高剂量的多种抗生素化疗,但他在4周后死亡,未确定感染病原体。尸检和微生物学检查显示为由星形诺卡菌引起的全身性化脓性感染。建议在临床症状出现后的前10天内进行经皮或开放性肺活检,以确保诊断并使用磺胺类药物进行治疗。

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