Innovation Center for Advanced Brewing Science and Technology, College of Biomass Science and Engineering, Sichuan University, Chengdu 610065, China.
Textile College, Changzhou Vocational Institute of Textile and Garment, Changzhou 213164, China.
Food Chem. 2024 Dec 1;460(Pt 3):140738. doi: 10.1016/j.foodchem.2024.140738. Epub 2024 Aug 3.
The biocompatible MIL-88A metal-organic framework (MOF), synthesized from food-grade fumaric acid and ferric chloride, was introduced for the efficient one-step in situ encapsulation of capsaicinoids as a nanopreservative. The resulting MIL-88A@Caps nanoparticles can load 61.43 mg/g of capsaicinoids, surpassing conventional MOF-based encapsulation. The potent MIL-88A@Caps nanoformulations synergize the intrinsic antimicrobial properties of MIL-88A and capsaicinoids. At the same concentration (0.5 mg/mL), MIL-88A@Caps was highly effective against S. aureus and Salmonella, with inhibition rates of 94.90 ± 0.58% and 94.30 ± 1.24%, respectively, compared to MIL-88A (62.28 ± 5.04% and 70.46 ± 1.96%) and capsaicinoids (63.68 ± 1.25% and 49.53 ± 1.22%), respectively. Model precooked-chicken preservation experiments revealed that MIL-88A@Caps significantly delayed spoilage parameters compared to untreated samples, with more favorable viable counts (8.08 lgCFU/g), pH value (6.60 ± 0.02), TVB-N value (8.59 ± 0.21 mg/100 g), and color changes on day 9. Our findings yield a green nanopreservative for meat safety.
由食品级富马酸和三氯化铁合成的生物相容性 MIL-88A 金属有机骨架（MOF）被引入用于高效一步原位封装辣椒素作为纳米防腐剂。所得的 MIL-88A@Caps 纳米颗粒可以负载 61.43mg/g 的辣椒素，超过了传统的 MOF 封装。有效的 MIL-88A@Caps 纳米制剂协同了 MIL-88A 和辣椒素的固有抗菌特性。在相同浓度（0.5mg/mL）下，MIL-88A@Caps 对金黄色葡萄球菌和沙门氏菌非常有效，抑制率分别为 94.90±0.58%和 94.30±1.24%，而 MIL-88A 的抑制率为 62.28±5.04%和 70.46±1.96%，辣椒素的抑制率为 63.68±1.25%和 49.53±1.22%。模型预煮鸡肉保鲜实验表明，与未处理样品相比，MIL-88A@Caps 显著延缓了变质参数，具有更有利的活菌数（8.08 lgCFU/g）、pH 值（6.60±0.02）、TVB-N 值（8.59±0.21mg/100g）和第 9 天的颜色变化。我们的研究结果为肉类安全提供了一种绿色的纳米防腐剂。
