Sydney School of Veterinary Science, The University of Sydney, Sydney, NSW, 2006, Australia.
Sydney Informatics Hub, The University of Sydney, Sydney, NSW, 2006, Australia.
Mamm Genome. 2024 Dec;35(4):556-564. doi: 10.1007/s00335-024-10059-y. Epub 2024 Aug 14.
Online Mendelian Inheritance in Animals (OMIA) is a freely available curated knowledgebase that contains information and facilitates research on inherited traits and diseases in animals. For the past 29 years, OMIA has been used by animal geneticists, breeders, and veterinarians worldwide as a definitive source of information. Recent increases in curation capacity and funding for software engineering support have resulted in software upgrades and commencement of several initiatives, which include the enhancement of variant information and links to human data resources, and the introduction of ontology-based breed information and categories. We provide an overview of current information and recent enhancements to OMIA and discuss how we are expanding the integration of OMIA into other resources and databases via the use of ontologies and the adaptation of tools used in human genetics.
在线孟德尔遗传数据库（OMIA）是一个免费提供的经过精心整理的知识库，其中包含有关动物遗传特征和疾病的信息，并为相关研究提供便利。在过去的 29 年中，OMIA 被全球的动物遗传学家、饲养员和兽医用作信息的权威来源。最近，由于对软件工程的支持进行了人员扩充和资金投入，我们对软件进行了升级，并启动了多个项目，其中包括增强了变体信息和与人的数据资源的链接，并引入了基于本体的品种信息和类别。我们提供了 OMIA 的当前信息和最近增强功能的概述，并讨论了我们如何通过使用本体和适应人类遗传学中使用的工具来扩展 OMIA 与其他资源和数据库的整合。
