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[影响血液透析动静脉移植物经皮腔内球囊血管成形术初始通畅时间的因素]

[Factors influencing primary patency time of percutaneous transluminal balloon angioplasty for hemodialysis arteriovenous grafts].

作者信息

Li X J, Zheng G F, Zhao X, Sun H, Fu Q N

机构信息

Department of Vascular Surgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing 401122, China.

Department of Vascular Surgery, Ganzhou People' Hospital, Ganzhou 341000, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2024 Aug 20;104(32):3037-3041. doi: 10.3760/cma.j.cn112137-20240318-00603.

DOI:10.3760/cma.j.cn112137-20240318-00603
PMID:39143771
Abstract

To investigate the factors affecting primary patency time in arteriovenous graft (AVG) patients receiving percutaneous transluminal balloon angioplasty (PTA). Hemodialysis patients who underwent AVG placement at the First Affiliated Hospital of Chongqing Medical University between February 2018 and December 2021 were included. The factors including age, gender, total duration of AVG use, site of stenosis, degree of stenosis, length of stenosis, residual stenosis, and presence of thrombosis were analyzed, and influencing factors of primary patency time in AVG were determined using a multiple linear regression model. A total of 101 patients who underwent 331 PTA treatments were enrolled, including 35 males and 66 females. The median age of patients undergoing PTA for the first time was 61 (51, 68) years, and the primary patency time after PTA was 5 (3, 10) months. The patients were followed up for (38.5±15.3) months. Multivariable linear regression analysis revealed that severe stenosis at the venous anastomosis and reflux veins (β=-2.773, 95%:-5.440--0.105, =0.042), female (β=-2.247, 95%:-3.853--0.642, =0.006), and previous multiple PTA treatments (β=-0.516, 95%:-0.978--0.054, =0.029) were risk factors for a shorter primary patency time after PTA. Severity of stenosis at the venous anastomosis and reflux veins of the AVG, female, and a history of multiple previous PTA treatments are associated with a shorter primary patency time in AVG patients.

摘要

探讨影响接受经皮腔内球囊血管成形术(PTA)的动静脉移植物(AVG)患者初次通畅时间的因素。纳入2018年2月至2021年12月在重庆医科大学附属第一医院接受AVG植入的血液透析患者。分析年龄、性别、AVG使用总时长、狭窄部位、狭窄程度、狭窄长度、残余狭窄及血栓形成情况等因素,采用多元线性回归模型确定AVG初次通畅时间的影响因素。共纳入101例接受331次PTA治疗的患者,其中男性35例,女性66例。首次接受PTA治疗患者的中位年龄为61(51,68)岁,PTA术后初次通畅时间为5(3,10)个月。患者随访时间为(38.5±15.3)个月。多变量线性回归分析显示,静脉吻合口和反流静脉重度狭窄(β=-2.773,95%:-5.440--0.105,P=0.042)、女性(β=-2.247,95%:-3.853--0.642,P=0.006)及既往多次PTA治疗(β=-0.516,95%:-0.978--0.054,P=0.029)是PTA术后初次通畅时间较短的危险因素。AVG静脉吻合口和反流静脉狭窄的严重程度、女性以及既往多次PTA治疗史与AVG患者较短的初次通畅时间相关。

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