Bu Chao, Zhang Mengdi, Sun Qihua, Zhang Hanxi, Luo Jing, Liu Qingyu, Sun Zhonghua, Li Yu
Department of Radiology, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, China.
Discipline of Medical Radiation Science, Curtin Medical School, Curtin University, Perth, Australia.
Quant Imaging Med Surg. 2024 Aug 1;14(8):6147-6160. doi: 10.21037/qims-24-462. Epub 2024 Jul 17.
Pulmonary artery aneurysm (PAA) is a rare pulmonary vascular disease with nonspecific symptoms and various etiologies. As the disease progresses, in addition to the dilation of the pulmonary arteries, it may be accompanied by remodeling of the cardiac structure and changes in the morphology of the aorta. Recognizing the cause of PAA is therefore a clinically challenging task. In this review article, we provide an overview of various causes of PAA with the support of corresponding imaging findings on computed tomography pulmonary angiography (CTPA) examination. Firstly, from the perspective of hemodynamics, a logical diagnosis is provided according to whether the main pulmonary artery (MPA) is dilated, and whether the PA is dilated locally or diffusely. Secondly, for the imaging examination of vascular wall lesions, due to the limitations of ultrasound examination and interventional procedures, the irreplaceability of dual-phase CTPA examination in disease assessment is especially emphasized. Finally, for highly suspected disorders, it is necessary to comprehensively check with the patient whether there is a family history or past medical history. For patients with PAA, especially those with Marfan syndrome (MFS) or arteritis, adequate preoperative imaging evaluation, regular postoperative radiographic follow-up, and concurrent treatment of the underlying disease (if necessary) are crucial, which are related to the prognosis and long-term quality of life of such patients. Despite the nonspecific features of PAA presentation, a thorough examination of the patient's clinical history and imaging characteristics will play an important role in diagnosing PAA and planning patient management strategies.
肺动脉瘤(PAA)是一种罕见的肺血管疾病,症状不具有特异性,病因多样。随着病情进展,除肺动脉扩张外,还可能伴有心脏结构重塑及主动脉形态改变。因此,明确PAA的病因是一项具有临床挑战性的任务。在这篇综述文章中,我们借助计算机断层扫描肺动脉造影(CTPA)检查的相应影像学表现,概述了PAA的各种病因。首先,从血流动力学角度,根据主肺动脉(MPA)是否扩张、肺动脉是局部扩张还是弥漫性扩张进行逻辑诊断。其次,对于血管壁病变的影像学检查,由于超声检查和介入操作的局限性,特别强调双期CTPA检查在疾病评估中的不可替代作用。最后,对于高度疑似的疾病,有必要全面询问患者是否有家族史或既往病史。对于PAA患者,尤其是患有马凡综合征(MFS)或动脉炎的患者,充分的术前影像学评估、术后定期的影像学随访以及必要时对基础疾病的同时治疗至关重要,这关系到此类患者的预后和长期生活质量。尽管PAA的表现缺乏特异性,但对患者临床病史和影像学特征进行全面检查,将对PAA的诊断及制定患者管理策略发挥重要作用。