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机器人辅助纵隔异位甲状旁腺切除术:单机构经验及胸外科手术回顾

Robotic-assisted ectopic mediastinal parathyroidectomy: a single institution experience and operative review for the thoracic surgeon.

作者信息

Stuart Christina M, Chanes Nicolas, Dyas Adam R, Albuja Cruz Maria B, Raeburn Christopher D, McIntyre Robert C, Randhawa Simran K, David Elizabeth A, Mitchell John D, Meguid Robert A

机构信息

Division of Cardiothoracic Surgery, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Surgical Outcomes and Applied Research Program, Department of Surgery, University of Colorado School of Medicine, Aurora, CO, USA.

出版信息

J Thorac Dis. 2024 Jul 30;16(7):4128-4136. doi: 10.21037/jtd-23-1920. Epub 2024 Jul 5.

Abstract

BACKGROUND

Parathyroidectomy remains the only definitive cure for primary hyperparathyroidism (PHPT). In rare cases, ectopic hyperfunctioning glands are located in the mediastinum, necessitating a thoracic surgical approach. The objective of this project was to review a single high-volume institutional experience of this presentation, with specific attention to the use of a robotic-assisted thoracic surgery (RATS) approach.

METHODS

This was a single-center, 5-year retrospective cohort study. All patients who underwent RATS mediastinal mass resection (MMR) for PHPT at the University of Colorado Anschutz Medical Campus were targeted for inclusion. Patient cases were reviewed for demographics, history, operative data, laboratory values, and postoperative course.

RESULTS

Eight patients underwent RATS-MMR for PHPT between 2018-2023. Median [interquartile range] operative time was 178 [138-213] minutes, and length of stay was 2.0 [1.5-2.0] days. One patient experienced post-operative chylothorax requiring dietary modification. There were no other 30-day complications or readmissions. Final pathology confirmed intrathymic parathyroid tissue in all patients. All patients achieved cure of PHPT.

CONCLUSIONS

The robotic-assisted approach has low morbidity and associated hospital length of stay and can be safely used to cure PHPT. As this is a rare pathology with an infrequently utilized surgical approach, it is important to critically discuss the diagnostic evaluation and operative course, aimed at educating the thoracic surgeon who may encounter and assist in the management of these patients.

摘要

背景

甲状旁腺切除术仍然是原发性甲状旁腺功能亢进症(PHPT)的唯一根治方法。在罕见情况下,异位功能亢进性腺位于纵隔,需要采用胸外科手术方法。本项目的目的是回顾这种表现的单一高容量机构经验,特别关注机器人辅助胸外科手术(RATS)方法的使用。

方法

这是一项单中心、5年回顾性队列研究。纳入所有在科罗拉多大学安舒茨医学校区接受RATS纵隔肿物切除术(MMR)治疗PHPT的患者。对患者病例进行人口统计学、病史、手术数据、实验室值和术后病程的回顾。

结果

2018年至2023年期间,8例患者接受了RATS-MMR治疗PHPT。中位[四分位间距]手术时间为178[138-213]分钟,住院时间为2.0[1.5-2.0]天。1例患者术后发生乳糜胸,需要调整饮食。没有其他30天并发症或再入院情况。最终病理证实所有患者均有胸腺内甲状旁腺组织。所有患者的PHPT均治愈。

结论

机器人辅助方法发病率低,住院时间短,可安全用于治愈PHPT。由于这是一种罕见的病理情况,手术方法使用不频繁,因此批判性地讨论诊断评估和手术过程很重要,目的是教育可能遇到并协助管理这些患者的胸外科医生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ec/11320283/a00d8f30a67f/jtd-16-07-4128-f1.jpg

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