Berkhout Suze G
Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.
University of Toronto Institute for the History & Philosophy of Science & Technology, Toronto, Ontario, Canada.
Schizophr Bull Open. 2022 Oct 18;3(1):sgac051. doi: 10.1093/schizbullopen/sgac051. eCollection 2022 Jan.
This short introduction provides a historical and ethical overview of placebos and placebo controls in relation to schizophrenia research, with a focus on long-term clinical trials. Drawing on historical and philosophical scholarship, it sketches a two-level analysis of ethical issues that placebos and the placebo effect raise for the field, particularly in light of shifts in clinical trial methodologies and clinical practices.
本简短介绍提供了与精神分裂症研究相关的安慰剂及安慰剂对照的历史与伦理概述,重点关注长期临床试验。借鉴历史和哲学学术成果,它勾勒了安慰剂及安慰剂效应给该领域带来的伦理问题的两级分析,特别是鉴于临床试验方法和临床实践的转变。