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寻找平衡:克罗恩病便血期间的静脉血栓栓塞预防

Finding the Balance: Venous Thromboembolism Prophylaxis during Hematochezia in Crohn's Disease.

作者信息

Kim Kain, Llanos Danielle, Ramos Christopher, Shahnavaz Nikrad, Adhyaru Bhavin B

机构信息

Department of Internal Medicine, Emory University School of Medicine, Atlanta, GA, USA.

Division of Vascular Surgery and Endovascular Therapy, Emory University School of Medicine, Atlanta, GA, USA.

出版信息

Case Rep Gastroenterol. 2024 Jul 22;18(1):367-372. doi: 10.1159/000540128. eCollection 2024 Jan-Dec.

Abstract

INTRODUCTION

Despite heightened risk of venous thromboembolism (VTE) in hospitalized patients with inflammatory bowel disease (IBD), pharmacologic prophylaxis remains underutilized, particularly in those presenting with hematochezia. Although placement of retrievable inferior vena cava filters (rIVCF) may be considered in those with contraindications to anticoagulation and VTE risk, current recommendations from clinical guidelines are incongruent, leading to wide variation in practice.

CASE PRESENTATION

This report highlights a case of rIVCF used in the management of recurrent VTEs in a patient hospitalized for persistent gastrointestinal bleeding.

CONCLUSION

Our case demonstrates the need for a lower threshold for initiating VTE prophylaxis in patients with active IBD, even when hematochezia is the presenting symptom. A small group of patients with recurrent VTE and clear contraindications to anticoagulation may require IVCFs, necessitating close follow-up and monitoring for filter complications.

摘要

引言

尽管炎症性肠病(IBD)住院患者发生静脉血栓栓塞症(VTE)的风险增加,但药物预防措施的使用仍然不足,尤其是在出现便血的患者中。虽然对于有抗凝禁忌和VTE风险的患者可考虑放置可回收下腔静脉滤器(rIVCF),但临床指南的当前建议并不一致,导致实践中的差异很大。

病例报告

本报告重点介绍了一名因持续性胃肠道出血住院的患者使用rIVCF治疗复发性VTE的病例。

结论

我们的病例表明,对于活动性IBD患者,即使以便血为主要症状,启动VTE预防的阈值也需要降低。一小部分复发性VTE且有明确抗凝禁忌的患者可能需要IVCF,这需要密切随访并监测滤器并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c47/11324262/f9d2cb9f1dcb/crg-2024-0018-0001-540128_F01.jpg

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