Durand L, Resal R, Burillon C
J Fr Ophtalmol. 1985;8(11):729-34.
The present study tries to point out new ideas about lattice corneal dystrophy. From our own observations we distinguish five clinical stages corresponding to each decade of life. We discuss the pathogenesis of the disease and the new histochemical and microscopical methods, and we emphasize on surgical treatment. In fact, surgery must be performed late in life and penetrating keratoplasty has become the treatment of choice. However, some authors describe recurrence of clinical signs of the dystrophy in penetrating grafts. In our study of thirty patients (between 1974 and 1984) including histopathologic evidences (66 procedures including 40 penetrating and 26 lamellar keratoplasties), did not find any single case of recurrence after penetrating keratoplasty.
本研究试图指出关于格子状角膜营养不良的新观点。根据我们自己的观察,我们区分出与每十年生命相对应的五个临床阶段。我们讨论了该疾病的发病机制以及新的组织化学和显微镜检查方法,并强调了手术治疗。事实上,手术必须在患者晚年进行,穿透性角膜移植术已成为首选治疗方法。然而,一些作者描述了穿透性移植物中营养不良临床症状的复发情况。在我们对30例患者(1974年至1984年期间)的研究中,包括组织病理学证据(66次手术,包括40次穿透性角膜移植术和26次板层角膜移植术),未发现穿透性角膜移植术后有任何一例复发。